MP:0000428 | abnormal craniofacial morphology | "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Terttm1Sear/Terttm1Sear Genetic Background: involves: 129S4/SvJae * C57BL/6
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MP:0000547 | short limbs | "reduced average length of the extremities" [MGI:CLS, J:61509] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
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MP:0000550 | abnormal forelimb morphology | "malformation of the entire anterior extremities" [MGI:tc] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
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MP:0000556 | abnormal hindlimb morphology | "malformation of the entire posterior extremities" [MGI:tc] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
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MP:0000565 | oligodactyly | "congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
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MP:0001147 | small testis | "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959] |
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Allelic Composition: Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk Genetic Background: involves: 129S2/SvPas
Allelic Composition: Cyp26b1tm1Ptk/Cyp26b1tm1Ptk,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0001152 | Leydig cell hyperplasia | "increased number of interstitial cells of the seminiferous tubules that secrete testosterone" [J:45065] |
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Allelic Composition: Cyp26b1tm1Ptk/Cyp26b1tm1Ptk,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0001153 | small seminiferous tubules | "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844] |
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Allelic Composition: Cyp26b1tm1Ptk/Cyp26b1tm1Ptk,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
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Allelic Composition: Cyp26b1tm1Ptk/Cyp26b1tm1Ptk,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0001216 | abnormal epidermal layer morphology | "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex Genetic Background: involves: 129S5/SvEvBrd * C57BL/6
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MP:0001231 | abnormal basal cell layer morphology | "structural anomaly of the deepest layer of the epidermis, which is composed of dividing stem cells and anchoring cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex Genetic Background: involves: 129S5/SvEvBrd * C57BL/6
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MP:0001240 | abnormal cornified layer morphology | "structural or developmental anomaly of the outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex Genetic Background: involves: 129S5/SvEvBrd * C57BL/6
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MP:0001302 | eyelids open at birth | "widely open eyes instead of closed at perinatal stage" [J:51966] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
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MP:0001648 | abnormal apoptosis | "excessive or absent cell death in a particular tissue or cell type" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:25248] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
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MP:0001672 | abnormal embryogenesis/ development | "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Rp1m1Jdun/Rp1m1Jdun Genetic Background: C57BL/6-Rp1m1Jdun
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MP:0001705 | abnormal proximal-distal axis patterning | "anomaly in the formation or development of a body structure, often a limb, in relation to the structure s proximity to the trunk or point of origin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
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MP:0001786 | skin edema | "accumulation of an excessive amount of fluid in the skin" [J:65039] |
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Allelic Composition: Sun1tm1.1Ktj/Sun1+,Sun2tm1.1Cyh/Sun2tm1.1Cyh Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6N
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MP:0001879 | abnormal lymphatic vessel morphology | "malformation of the network of vessels which carries lymph around the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
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Allelic Composition: Sun1tm1.1Ktj/Sun1+,Sun2tm1.1Cyh/Sun2tm1.1Cyh Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6N
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MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Sun1tm1.1Ktj/Sun1+,Sun2tm1.1Cyh/Sun2tm1.1Cyh Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6N
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MP:0001954 | respiratory distress | "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
Allelic Composition: Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk Genetic Background: involves: 129S2/SvPas
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MP:0002085 | abnormal embryonic tissue morphology | "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Rp1m1Jdun/Rp1m1Jdun Genetic Background: C57BL/6-Rp1m1Jdun
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MP:0002109 | abnormal limb morphology | "abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
Allelic Composition: Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk Genetic Background: involves: 129S2/SvPas
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MP:0002115 | abnormal skeleton extremities morphology | "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
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MP:0002216 | abnormal seminiferous tubule morphology | "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cyp26b1tm1Ptk/Cyp26b1tm1Ptk,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0002639 | micrognathia | "abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
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MP:0002796 | impaired skin barrier function | "impaired ability of the skin to regulate water loss; frequently leads to dehydration" [J:56641] |
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Allelic Composition: Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex Genetic Background: involves: 129S5/SvEvBrd * C57BL/6
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MP:0003704 | abnormal hair follicle development | "anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex Genetic Background: involves: 129S5/SvEvBrd * C57BL/6
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MP:0004901 | decreased male germ cell number | "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk Genetic Background: involves: 129S2/SvPas
Allelic Composition: Cyp26b1tm1Ptk/Cyp26b1tm1Ptk,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0005169 | abnormal male meiosis | "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Cyp26b1tm1Ptk/Cyp26b1tm1Ptk,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
Allelic Composition: Cyp26b1tm1Dcp/Cyp26b1tm1Dcp Genetic Background: involves: 129S4/SvJae * C57BL/6
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MP:0006279 | abnormal limb development | "anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex Genetic Background: involves: 129S5/SvEvBrd * C57BL/6
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MP:0008280 | male germ cell apoptosis | "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk Genetic Background: involves: 129S2/SvPas
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MP:0009594 | abnormal corneocyte envelope morphology | "any structural or developmental anomaly of the electron-dense layer of highly transglutaminase cross-linked protein that is deposited on the inner surface of the plasma membrane of corneocytes in the outermost layers of the epidermis; a monomolecular layer of ceramides is covalently attached to the outer surface of the CE to form a hydrophobic lipid envelope that covers each corneocyte and provides continuity with the lipid matrix" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex Genetic Background: involves: 129S5/SvEvBrd * C57BL/6
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MP:0009603 | absent keratohyalin granules | "absence of the irregularly shaped basophilic granules in the cells of the stratum granulosum of the epidermis that may play a role in keratinization and barrier function" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex Genetic Background: involves: 129S5/SvEvBrd * C57BL/6
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MP:0010197 | abnormal lymphatic vessel endothelial cell morphology | "any structural anomaly of the cells that line the lymphatic vessels" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Limk2Gt(OST80053)Lex/Limk2Gt(OST80053)Lex Genetic Background: involves: 129S5/SvEvBrd * C57BL/6
Allelic Composition: Cyp26b1tm1Hh/Cyp26b1tm1Hh,Tg(Prox1-EGFP)KY221Gsat/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/NTac
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
Allelic Composition: Cyp26b1tm1.1Ptk/Cyp26b1tm1.1Ptk Genetic Background: involves: 129S2/SvPas
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MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Cyp26b1tm1Dcp/Cyp26b1tm1Dcp Genetic Background: involves: 129S4/SvJae * C57BL/6
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MP:0014106 | delayed chondrocyte differentiation | "delay in the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte" [GO:0002062] |
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid Genetic Background: involves: 129S1/SvImJ * C57BL/6J
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