ENSMUSG00000066072
Mus musculus activity Cyp4a10 membrane cytochrome p process ion binding fatty acid endoplasmic reticulum organelle oxidoreductase -monooxygenase acids synthesis hypertension decreased renal sodium e-class group conserved site superfamily metabolic leukotriene b catabolic oxidation-reduction
Features Gene ID: ENSMUSG00000066072 Biological name :Cyp4a10 Synonyms : Cyp4a10 / Cytochrome P450 4A10 / O88833 Possible biological names infered from orthology : CYP4A11 / CYP4A22 / cytochrome P450 family 4 subfamily A member 11 / cytochrome P450 family 4 subfamily A member 22 / Q02928 / Q5TCH4 Species: Mus musculus Chr. number: 4 Strand: 1 Band: D1 Gene start: 115518264 Gene end: 115533649 Corresponding Affymetrix probe sets: 10507163 (MoGene1.0st) 10507177 (MoGene1.0st) 1424853_s_at (Mouse Genome 430 2.0 Array) Cross references: Ensembl peptide - ENSMUSP00000092486 Ensembl peptide - ENSMUSP00000061126 NCBI entrez gene - 13117
See in Manteia .
MGI - MGI:88611 RefSeq - NM_010011 RefSeq Peptide - NP_034141 swissprot - A2A977 swissprot - O88833 Ensembl - ENSMUSG00000066072
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) Cyp4a32 / cytochrome P450, family 4, subfamily a, polypeptide 32 / Q5TCH4* / Q02928* / CYP4A11* / CYP4A22* / cytochrome P450 family 4 subfamily A member 22* / cytochrome P450 family 4 subfa... ENSMUSG00000063929 96 Cyp4a31 / cytochrome P450, family 4, subfamily a, polypeptide 31 / Q5TCH4* / Q02928* / CYP4A11* / CYP4A22* / cytochrome P450 family 4 subfamily A member 22* / cytochrome P450 family 4 subfa... ENSMUSG00000028712 94 Cyp4a12b / cytochrome P450, family 4, subfamily a, polypeptide 12B / Q5TCH4* / Q02928* / CYP4A11* / CYP4A22* / cytochrome P450 family 4 subfamily A member 22* / cytochrome P450 family 4 sub... ENSMUSG00000078597 78 Q91WL5 / Cyp4a12a / Cytochrome P450 4A12A / Q02928* / Q5TCH4* / CYP4A11* / CYP4A22* / cytochrome P450 family 4 subfamily A member 22* / cytochrome P450 family 4 subfamily A member 11* ENSMUSG00000066071 77 O35728 / Cyp4a14 / Cytochrome P450 4A14 / Q5TCH4* / Q02928* / CYP4A11* / CYP4A22* / cytochrome P450 family 4 subfamily A member 22* / cytochrome P450 family 4 subfamily A member 11* ENSMUSG00000028715 71 Cyp4a29 / cytochrome P450, family 4, subfamily a, polypeptide 29 / Q5TCH4* / Q02928* / CYP4A11* / CYP4A22* / cytochrome P450 family 4 subfamily A member 22* / cytochrome P450 family 4 subfa... ENSMUSG00000083138 69 Cyp4a30b / cytochrome P450, family 4, subfamily a, polypeptide 30b / Q5TCH4* / Q02928* / CYP4A11* / CYP4A22* / cytochrome P450 family 4 subfamily A member 22* / cytochrome P450 family 4 sub... ENSMUSG00000084346 69 Cyp4b1 / Q64462 / Cytochrome P450 4B1 / P13584* / cytochrome P450 family 4 subfamily B member 1* ENSMUSG00000028713 52 Cyp4x1 / Q6A152 / Cytochrome P450 4X1 / Q8N118* / cytochrome P450 family 4 subfamily X member 1* ENSMUSG00000047155 50 Q99N16 / Cyp4f18 / Leukotriene-B(4) omega-hydroxylase 2 / CYP4F3* / Q08477* / cytochrome P450 family 4 subfamily F member 3* ENSMUSG00000003484 45 Cyp4f13 / cytochrome P450, family 4, subfamily f, polypeptide 13 ENSMUSG00000024055 44 Q9EP75 / Cyp4f14 / Mus musculus cytochrome P450, family 4, subfamily f, polypeptide 14 (Cyp4f14), transcript variant 6, mRNA. ENSMUSG00000024292 44 Cyp4f15 / cytochrome P450, family 4, subfamily f, polypeptide 15 ENSMUSG00000073424 44 Cyp4f40 / cytochrome P450, family 4, subfamily f, polypeptide 40 ENSMUSG00000090700 44 Cyp4f17 / cytochrome P450, family 4, subfamily f, polypeptide 17 ENSMUSG00000091586 44 Cyp4f16 / cytochrome P450, family 4, subfamily f, polypeptide 16 ENSMUSG00000048440 43 Cyp4f39 / cytochrome P450, family 4, subfamily f, polypeptide 39 / Q6NT55* / CYP4F22* / cytochrome P450 family 4 subfamily F member 22* ENSMUSG00000061126 42 Cyp4f37 / cytochrome P450, family 4, subfamily f, polypeptide 37 ENSMUSG00000062464 42 Q9DBW0 / Cyp4v3 / Cytochrome P450 4V2 / CYP4V2* / Q6ZWL3* / cytochrome P450 family 4 subfamily V member 2* ENSMUSG00000079057 31
Protein motifs (from Interpro )
Gene Ontology (GO ) cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process catabolic process oxidation-reduction process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process catabolic process oxidation-reduction process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process catabolic process oxidation-reduction process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process catabolic process oxidation-reduction process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process catabolic process oxidation-reduction process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process catabolic process oxidation-reduction process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process catabolic process oxidation-reduction process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process catabolic process oxidation-reduction process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process catabolic process oxidation-reduction process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process catabolic process oxidation-reduction process cellular metabolic proccellular metabolic process primary metabolic proceprimary metabolic process small molecule metabolismall molecule metabolic process organic substance metaborganic substance metabolic process catabolic processcatabolic process oxidation-reduction prooxidation-reduction process oxidoreductase activity ion binding organic cyclic compound binding heterocyclic compound binding cofactor binding oxidoreductase activity ion binding organic cyclic compound binding heterocyclic compound binding cofactor binding oxidoreductase activity ion binding organic cyclic compound binding heterocyclic compound binding cofactor binding oxidoreductase activity ion binding organic cyclic compound binding heterocyclic compound binding cofactor binding oxidoreductase activity ion binding organic cyclic compound binding heterocyclic compound binding cofactor binding oxidoreductase activity ion binding organic cyclic compound binding heterocyclic compound binding cofactor binding oxidoreductase activity ion binding organic cyclic compound binding heterocyclic compound binding cofactor binding oxidoreductase activity ion binding organic cyclic compound binding heterocyclic compound binding cofactor binding oxidoreductase activity ion binding organic cyclic compound binding heterocyclic compound binding cofactor binding oxidoreductase activity ion binding organic cyclic compound binding heterocyclic compound binding cofactor binding oxidoreductase activityoxidoreductase activity ion bindingion binding organic cyclic compound bindorganic cyclic compound binding heterocyclic compound bindinheterocyclic compound binding cofactor bindingcofactor binding cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cellcell organelleorganelle membranemembrane
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO ) cardiovascular system phenotype growth/size phenotype renal/urinary system phenotype homeostasis/metabolism phenotype cardiovascular system phenotype growth/size phenotype renal/urinary system phenotype homeostasis/metabolism phenotype cardiovascular system phenotype growth/size phenotype renal/urinary system phenotype homeostasis/metabolism phenotype cardiovascular system phenotype growth/size phenotype renal/urinary system phenotype homeostasis/metabolism phenotype cardiovascular system phenotype growth/size phenotype renal/urinary system phenotype homeostasis/metabolism phenotype cardiovascular system phenotype growth/size phenotype renal/urinary system phenotype homeostasis/metabolism phenotype cardiovascular system phenotype growth/size phenotype renal/urinary system phenotype homeostasis/metabolism phenotype cardiovascular system phenotype growth/size phenotype renal/urinary system phenotype homeostasis/metabolism phenotype cardiovascular system phenotype growth/size phenotype renal/urinary system phenotype homeostasis/metabolism phenotype cardiovascular system phenotype growth/size phenotype renal/urinary system phenotype homeostasis/metabolism phenotype cardiovascular system phenotypecardiovascular system phenotype growth/size phenotypegrowth/size phenotype renal/urinary system phenotyperenal/urinary system phenotype homeostasis/metabolism phenotypehomeostasis/metabolism phenotype MP:0000231 hypertension "sustained high blood pressure at a level that is likely to result in cardiovascular disease and/or other pathological states" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ednrbtm1Myks /Ednrbtm1Myks Genetic Background: involves: 129P2/OlaHsd
MP:0000676 abnormal water content "more or less than the normal total amount of water retained in the body" [il:Ira Lu, Mouse Genome Informatics Curator]
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Allelic Composition: Ednrbtm1Myks /Ednrbtm1Myks Genetic Background: involves: 129P2/OlaHsd
MP:0003620 decreased urine output "decreased volume of urine produced and excreted" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Ednrbtm1Myks /Ednrbtm1Myks Genetic Background: involves: 129P2/OlaHsd
MP:0004217 salt-sensitive hypertension "sustained high blood pressure that is maintained with a normal or increase in the amount of salt consumed in the diet; blood pressure may return to normotensive with a low salt diet" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ednrbtm1Myks /Ednrbtm1Myks Genetic Background: involves: 129P2/OlaHsd
MP:0005618 decreased potassium excretion "less than the normal amount of this alkaline metallic element, the most abundant intracellular ion, voided by the kidneys" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Ednrbtm1Myks /Ednrbtm1Myks Genetic Background: involves: 129P2/OlaHsd
MP:0006144 increased systolic blood pressure "abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Ednrbtm1Myks /Ednrbtm1Myks Genetic Background: involves: 129P2/OlaHsd
MP:0010109 abnormal renal sodium reabsorption "any anomaly in the process by which sodium ions are transported out of the renal tubules back into the bloodstream" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Ednrbtm1Myks /Ednrbtm1Myks Genetic Background: involves: 129P2/OlaHsd
MP:0011442 abnormal renal sodium ion transport "any anomaly in the directed movement of sodium ions (Na+) by the kidney" [GO:0003096]
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Allelic Composition: Ednrbtm1Myks /Ednrbtm1Myks Genetic Background: involves: 129P2/OlaHsd
Interacting proteins (from Reactome )No match
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