ENSMUSG00000074155


Mus musculus

Features
Gene ID: ENSMUSG00000074155
  
Biological name :Klk5
  
Synonyms : kallikrein related-peptidase 5 / Klk5
  
Possible biological names infered from orthology : Q9Y337
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 43841971
Gene end: 43851181
  
Corresponding Affymetrix probe sets: 10552526 (MoGene1.0st)   1429230_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000049339
Ensembl peptide - ENSMUSP00000145643
NCBI entrez gene - 68668     See in Manteia.
MGI - MGI:1915918
RefSeq - XM_006541152
RefSeq - NM_026806
RefSeq - XM_006541150
RefSeq - XM_006541151
RefSeq Peptide - NP_081082
swissprot - A0A0U1RNP0
swissprot - Q9D140
Ensembl - ENSMUSG00000074155
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000034771Gallus gallus
 KLK5ENSG00000167754Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klk12 / kallikrein related peptidase 12 / Q9UKR0*ENSMUSG0000004443037
Klk4 / Q9Z0M1 / Kallikrein-4 / Q9Y5K2* / kallikrein related peptidase 4*ENSMUSG0000000694835
Klk7 / Q91VE3 / Kallikrein-7 / P49862* / kallikrein related peptidase 7*ENSMUSG0000003071334
Klk10 / kallikrein related peptidase 10 / O43240*ENSMUSG0000003069327


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002803 positive regulation of antibacterial peptide production ISO
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway ISO
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0097209 epidermal lamellar body ISO
 molecular_functionGO:0004252 serine-type endopeptidase activity ISO
 molecular_functionGO:0008233 peptidase activity ISO
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031995 St14 / P56677 / suppression of tumorigenicity 14 (colon carcinoma) / Q9Y5Y6* / suppression of tumorigenicity 14*  / reaction
 ENSMUSG00000055095 Q8BT20 / Spink6 / serine peptidase inhibitor, Kazal type 6 / Q6UWN8*  / complex / reaction
 ENSMUSG00000064023 Klk8 / Q61955 / Kallikrein-8 / O60259* / kallikrein related peptidase 8*  / reaction
 ENSMUSG00000058579 Cela2a / P05208 / Chymotrypsin-like elastase family member 2A / CELA2B* / P08218* / P08217* / chymotrypsin like elastase family member 2B*  / reaction
 ENSMUSG00000055561 Spink5 / serine peptidase inhibitor, Kazal type 5 / Q9NQ38*  / complex / reaction






 

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