ENSMUSG00000079036


Mus musculus

Features
Gene ID: ENSMUSG00000079036
  
Biological name :Alkbh1
  
Synonyms : Alkbh1 / Nucleic acid dioxygenase ALKBH1 / P0CB42
  
Possible biological names infered from orthology : alkB homolog 1, histone H2A dioxygenase / Q13686
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: D2
Gene start: 87425840
Gene end: 87444017
  
Corresponding Affymetrix probe sets: 10401795 (MoGene1.0st)   1434660_at (Mouse Genome 430 2.0 Array)   1438681_at (Mouse Genome 430 2.0 Array)   1440263_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124565
Ensembl peptide - ENSMUSP00000124691
Ensembl peptide - ENSMUSP00000140233
Ensembl peptide - ENSMUSP00000125372
Ensembl peptide - ENSMUSP00000124933
Ensembl peptide - ENSMUSP00000124892
Ensembl peptide - ENSMUSP00000124360
Ensembl peptide - ENSMUSP00000124445
NCBI entrez gene - 211064     See in Manteia.
NCBI entrez gene - 654309     See in Manteia.
MGI - MGI:2384034
RefSeq - NM_001102565
RefSeq - NM_001013372
RefSeq Peptide - NP_001013390
RefSeq Peptide - NP_001096035
swissprot - P0CB42
swissprot - E0CZH7
swissprot - Q5XLJ1
swissprot - E0CYA7
swissprot - E0CY72
swissprot - E0CX46
swissprot - F6U5G1
Ensembl - ENSMUSG00000079036
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 alkbh1ENSDARG00000071164Danio rerio
 ALKBH1ENSGALG00000010485Gallus gallus
 ALKBH1ENSG00000100601Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004574  Alkylated DNA repair protein AlkB
 IPR005123  Oxoglutarate/iron-dependent dioxygenase
 IPR027450  Alpha-ketoglutarate-dependent dioxygenase AlkB-like
 IPR037151  Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001764 neuron migration IDA
 biological_processGO:0001890 placenta development IMP
 biological_processGO:0002101 tRNA wobble cytosine modification IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006307 DNA dealkylation involved in DNA repair IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006446 regulation of translational initiation IEA
 biological_processGO:0006448 regulation of translational elongation IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0030154 cell differentiation IMP
 biological_processGO:0031175 neuron projection development IDA
 biological_processGO:0035552 oxidative single-stranded DNA demethylation IBA
 biological_processGO:0042245 RNA repair ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process IDA
 biological_processGO:0048589 developmental growth IMP
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070129 regulation of mitochondrial translation IEA
 biological_processGO:0070989 oxidative demethylation IEA
 biological_processGO:0080111 DNA demethylation IEA
 biological_processGO:1990983 tRNA demethylation IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005719 nuclear euchromatin IDA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008198 ferrous iron binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0042056 chemoattractant activity IDA
 molecular_functionGO:0043734 DNA-N1-methyladenine dioxygenase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA
 molecular_functionGO:0070579 methylcytosine dioxygenase activity IEA
 molecular_functionGO:0103053 1-ethyladenine demethylase activity IEA
 molecular_functionGO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
 molecular_functionGO:0140080 class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
 molecular_functionGO:1990984 tRNA demethylase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000077 abnormal interparietal bone morphology "malformed bone of the cranium; lies above and anterior to the occipital bone " [J:61509]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0000107 abnormal frontal bone morphology "malformed bone forming the forehead and part of the eye orbit" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0000109 abnormal parietal bone morphology "malformed curved bone forming part of the vault of the cranium" [J:17489]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0000116 abnormal tooth development "anomalous formation of the teeth" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0000157 abnormal sternum morphology "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0000445 short snout "reduced length of the anterior facial part of the muzzle" [J:53370]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Alkbh1tm1Klng/Alkbh1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000458 abnormal mandible morphology "malformation of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Alkbh1tm1Klng/Alkbh1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001293 anophthalmia "congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Alkbh1tm1Klng/Alkbh1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Alkbh1tm1Klng/Alkbh1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001326 retinal degeneration "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001328 disorganized retinal layers "delaminated or mispositioned sheets of cells comprising the optic part of the retina" [J:33400]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001713 reduced trophoblast cell number "fewer than normal number of cells of the extraembryonic cell layer that contributes to the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:23171]
Show

Allelic Composition: Nfasctm1.1Brp/Nfasctm1.1Brp,Tg(Plp1-Nfasc*)1Brp/0
Genetic Background: B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001915 intracranial hemorrhage "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Alkbh1tm1Klng/Alkbh1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0002840 abnormal lens fibers morphology "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0003072 abnormal metatarsal bone morphology "anomaly in the five bones of the hindpaws that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0003078 aphakia "absence of the crystalline lens of the eye" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0003420 delayed intramembranous bone ossification "late onset of bone formation in bones that form without a cartilagenous intermediate including the cranium and clavicle" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0003720 abnormal neural tube closure "abnormal invagination and fusion of the neuroepithelial layer in early development" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:99099]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Alkbh1tm1Klng/Alkbh1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004200 reduced fetal size "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nfasctm1.1Brp/Nfasctm1.1Brp,Tg(Plp1-Nfasc*)1Brp/0
Genetic Background: B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004201 fetal growth retardation "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nfasctm1.1Brp/Nfasctm1.1Brp,Tg(Plp1-Nfasc*)1Brp/0
Genetic Background: B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp

 MP:0004266 pale placenta "placenta lacking normal reddish coloration, often refers to bloodless condition" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nfasctm1.1Brp/Nfasctm1.1Brp,Tg(Plp1-Nfasc*)1Brp/0
Genetic Background: B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp

 MP:0004380 short frontal bone "reduced length of the bone forming the forehead and roof of the eye orbit" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004471 short nasal bone "reduced length of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004473 absent nasal bone "absence of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004921 decreased placenta weight "reduction in the weight of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nfasctm1.1Brp/Nfasctm1.1Brp,Tg(Plp1-Nfasc*)1Brp/0
Genetic Background: B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp

 MP:0005263 ectopia lentis "congenital displacement of the lens due to defective zonule formation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005306 abnormal phalanx morphology "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col1a1tm1(tetO-mCherry)Eggn/Col1a1tm1(tetO-mCherry)Eggn
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0008277 abnormal sternum ossification "anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Alkbh1tm1Klng/Alkbh1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0008957 abnormal placenta junctional zone morphology "fetally derived placental region that separates the maternal uterine tissue from the placenta labyrinth" [PMID:16367805]
Show

Allelic Composition: Nfasctm1.1Brp/Nfasctm1.1Brp,Tg(Plp1-Nfasc*)1Brp/0
Genetic Background: B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp

 MP:0008959 abnormal spongiotrophoblast cell morphology "any structural anomaly of a trophoblast cell that arises in the junctional zone of the placenta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nfasctm1.1Brp/Nfasctm1.1Brp,Tg(Plp1-Nfasc*)1Brp/0
Genetic Background: B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp

 MP:0009674 decreased birth weight "reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"]
Show

Allelic Composition: Nfasctm1.1Brp/Nfasctm1.1Brp,Tg(Plp1-Nfasc*)1Brp/0
Genetic Background: B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp

 MP:0010743 delayed suture closure "late onset of the fusion of the bones of the skull" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0010769 abnormal survival "deviation from the expected viability or life span of an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Alkbh1tm1Klng/Alkbh1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0011521 decreased placental labyrinth size "reduction in the size of the structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [MGI:csmith]
Show

Allelic Composition: Nfasctm1.1Brp/Nfasctm1.1Brp,Tg(Plp1-Nfasc*)1Brp/0
Genetic Background: B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp

 MP:0012101 acoria "absence of the pupil of the eye" [MGI:anna]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0012109 decreased trophoblast glycogen cell number "reduced number of the glycogen-accumulating trophoblast cells that arise in the junctional zone of the placenta" [MGI:csmith]
Show

Allelic Composition: Nfasctm1.1Brp/Nfasctm1.1Brp,Tg(Plp1-Nfasc*)1Brp/0
Genetic Background: B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp

 MP:0020040 decreased bone ossification "decrease in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [ORCID: orcid.org/0000-0003-4606-0597]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0030029 wide cranial sutures "an abnormally increased width of one or more cranial sutures for age-related norms, generally resulting from delayed suture closure" [HP:0010537]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1tm1Klng
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0030189 broad snout "increased width of the anterior facial part of the face or muzzle containing the oral and nasal regions" [MGI:anna]
Show

Allelic Composition: Alkbh1tm1Klng/Alkbh1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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