ENSMUSG00000079547


Mus musculus

Features
Gene ID: ENSMUSG00000079547
  
Biological name :H2-DMb1
  
Synonyms : H2-DMb1 / histocompatibility 2, class II, locus Mb1
  
Possible biological names infered from orthology : AL645941.2 / HLA-DMB / major histocompatibility complex, class II, DM beta / P28068
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: B1
Gene start: 34153072
Gene end: 34160230
  
Corresponding Affymetrix probe sets: 1418638_at (Mouse Genome 430 2.0 Array)   1449580_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109870
NCBI entrez gene - 14999     See in Manteia.
MGI - MGI:95922
RefSeq - NM_010387
RefSeq Peptide - NP_034517
swissprot - Q31094
Ensembl - ENSMUSG00000079547
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU929676.1ENSDARG00000104635Danio rerio
 FO744840.1ENSDARG00000110501Danio rerio
 mhc2bENSDARG00000104730Danio rerio
 mhc2dabENSDARG00000079105Danio rerio
 mhc2dbbENSDARG00000056330Danio rerio
 si:busm1-104n07.3ENSDARG00000074510Danio rerio
 si:busm1-228j01.4ENSDARG00000088872Danio rerio
 si:busm1-228j01.6ENSDARG00000041705Danio rerio
 si:ch73-158p21.3ENSDARG00000101030Danio rerio
 si:zfos-2070c2.3ENSDARG00000076307Danio rerio
 zgc:103700ENSDARG00000116524Danio rerio
 ENSGALG00000044502Gallus gallus
 ENSGALG00000034319Gallus gallus
 BLB1ENSGALG00000000141Gallus gallus
 BLB2ENSGALG00000030940Gallus gallus
 AL645941.2ENSG00000248993Homo sapiens
 P28068ENSG00000242574Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
H2-DMb2 / histocompatibility 2, class II, locus Mb2 / P28068* / HLA-DMB* / AL645941.2* / major histocompatibility complex, class II, DM beta*ENSMUSG0000003754893
H2-Ob / histocompatibility 2, O region beta locus / P13765* / HLA-DOB* / major histocompatibility complex, class II, DO beta*ENSMUSG0000004153826
H2-Ab1 / P14483 / histocompatibility 2, class II antigen A, beta 1 / P05538* / HLA-DQB1* / HLA-DQB2* / major histocompatibility complex, class II, DQ beta 1* / major histocompatibility comp...ENSMUSG0000007342125
H2-Eb1 / Q9GIY3* / P01911* / P04229* / Q29974* / Q30154* / HLA-DRB5* / HLA-DRB1* / major histocompatibility complex, class II, DR beta 1* / major histocompatibility complex, class II, DR beta 5*ENSMUSG0000006058623
H2-Eb2 / Q9GIY3* / P01911* / P04229* / Q29974* / Q30154* / HLA-DRB5* / HLA-DRB1* / major histocompatibility complex, class II, DR beta 1* / major histocompatibility complex, class II, DR beta 5*ENSMUSG0000006734123


Protein motifs (from Interpro)
Interpro ID Name
 IPR000353  MHC class II, beta chain, N-terminal
 IPR003006  Immunoglobulin/major histocompatibility complex, conserved site
 IPR003597  Immunoglobulin C1-set
 IPR007110  Immunoglobulin-like domain
 IPR011162  MHC classes I/II-like antigen recognition protein
 IPR013783  Immunoglobulin-like fold
 IPR014745  MHC class II, alpha/beta chain, N-terminal
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0019882 antigen processing and presentation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042613 MHC class II protein complex IEA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000036594 H2-Aa / P14434 / H-2 class II histocompatibility antigen, A-B alpha chain / P01909* / P01906* / HLA-DQA2* / HLA-DQA1* / major histocompatibility complex, class II, DQ alpha 2* / major hist...  / complex / reaction
 ENSMUSG00000073421 H2-Ab1 / P14483 / histocompatibility 2, class II antigen A, beta 1 / P05538* / HLA-DQB1* / HLA-DQB2* / major histocompatibility complex, class II, DQ beta 1* / major histocompatibility comp...  / complex / reaction
 ENSMUSG00000024610 Cd74 / P04441 / CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) / P04233* / CD74 molecule*  / reaction
 ENSMUSG00000067341 H2-Eb2 / Q9GIY3* / P01911* / P04229* / Q29974* / Q30154* / HLA-DRB5* / HLA-DRB1* / major histocompatibility complex, class II, DR beta 1* / major histocompatibility complex, class II, DR beta 5*  / complex / reaction
 ENSMUSG00000060586 H2-Eb1 / Q9GIY3* / P01911* / P04229* / Q29974* / Q30154* / HLA-DRB5* / HLA-DRB1* / major histocompatibility complex, class II, DR beta 1* / major histocompatibility complex, class II, DR beta 5*  / complex / reaction
 ENSMUSG00000024334 H2-Oa / major histocompatibility complex, class II, DO alpha / P06340* / HLA-DOA*  / complex
 ENSMUSG00000037649 H2-DMa / histocompatibility 2, class II, locus DMa / P28067* / HLA-DMA* / major histocompatibility complex, class II, DM alpha*  / complex
 ENSMUSG00000041538 H2-Ob / histocompatibility 2, O region beta locus / P13765* / HLA-DOB* / major histocompatibility complex, class II, DO beta*  / complex






 

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