8301


Homo sapiens (NCBI)

Features
Gene ID: 8301
  
Biological name :
  
Synonyms : CALM|CLTH|LAP / phosphatidylinositol binding clathrin assembly protein / PICALM
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 203134_at (Human Genome U133 Plus 2.0 Array)   212506_at (Human Genome U133 Plus 2.0 Array)   212511_at (Human Genome U133 Plus 2.0 Array)   215236_s_at (Human Genome U133 Plus 2.0 Array)   215832_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 530397474
RefSeq - 1034575715
RefSeq - 1034575717
RefSeq - 1034575719
RefSeq - 1034575721
RefSeq - 1034575723
RefSeq - 1034575725
RefSeq - 1034575727
RefSeq - 1370460307
RefSeq - 332635087
RefSeq - 332688231
RefSeq - 530397444
RefSeq - 530397446
RefSeq - 530397448
RefSeq - 530397450
RefSeq - 530397452
RefSeq - 530397454
RefSeq - 530397456
RefSeq - 530397458
RefSeq - 530397460
RefSeq - 530397462
RefSeq - 530397464
RefSeq - 530397466
RefSeq - 530397468
RefSeq - 530397470
RefSeq - 530397472
RefSeq - 1034575712
RefSeq - 530397480
RefSeq - 56788366
RefSeq - 56788368
RefSeq - 578821765
RefSeq - 578821767
RefSeq - 578821769
RefSeq - 767968864
RefSeq - NC_000011.10
RefSeq - NG_028942.1
RefSeq - NP_001008660.1
RefSeq - NP_001193875.1
RefSeq - NP_001193876.1
RefSeq - NP_009097.2
RefSeq - XP_005274379.1
RefSeq - XP_005274380.1
RefSeq - XP_005274381.1
RefSeq - XP_005274382.1
RefSeq - XP_005274383.1
RefSeq - XP_005274384.1
RefSeq - XP_005274385.1
RefSeq - XP_005274386.1
RefSeq - XP_005274387.1
RefSeq - XP_005274388.1
RefSeq - XP_005274389.1
RefSeq - XP_005274390.1
RefSeq - XP_005274391.1
RefSeq - XP_005274392.1
RefSeq - XP_005274393.1
RefSeq - XP_005274394.1
RefSeq - XP_005274397.1
RefSeq - XP_006718762.1
RefSeq - XP_006718763.1
RefSeq - XP_006718764.1
RefSeq - XP_011543595.1
RefSeq - XP_016873870.1
RefSeq - XP_016873871.1
RefSeq - XP_016873872.1
RefSeq - XP_016873873.1
RefSeq - XP_016873874.1
RefSeq - XP_016873875.1
RefSeq - XP_016873876.1
RefSeq - XP_016873877.1
RefSeq - XP_024304468.1
RefSeq - NM_001008660.2
RefSeq - NM_001206946.1
RefSeq - NM_001206947.1
RefSeq - NM_007166.3
RefSeq - XM_017018386.2
RefSeq - XM_017018387.2
RefSeq - XM_017018388.2
RefSeq - XM_024448700.1
RefSeq - XM_005274322.3
RefSeq - XM_005274323.3
RefSeq - XM_005274324.3
RefSeq - XM_005274325.3
RefSeq - XM_005274326.3
RefSeq - XM_005274327.3
RefSeq - XM_005274328.3
RefSeq - XM_005274329.4
RefSeq - XM_005274330.3
RefSeq - XM_005274331.3
RefSeq - XM_005274332.3
RefSeq - XM_005274333.3
RefSeq - XM_005274334.3
RefSeq - XM_005274335.3
RefSeq - XM_005274336.3
RefSeq - XM_005274337.3
RefSeq - XM_005274340.3
RefSeq - XM_006718699.3
RefSeq - XM_006718700.3
RefSeq - XM_006718701.4
RefSeq - XM_011545293.2
RefSeq - XM_017018381.2
RefSeq - XM_017018382.2
RefSeq - XM_017018383.2
RefSeq - XM_017018384.2
RefSeq - XM_017018385.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000073921 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis ISS
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0007611 learning or memory ISS
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0016050 vesicle organization IMP
 biological_processGO:0016188 synaptic vesicle maturation ISS
 biological_processGO:0016192 vesicle-mediated transport TAS
 biological_processGO:0016197 endosomal transport IMP
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0030100 regulation of endocytosis IMP
 biological_processGO:0031623 receptor internalization IMP
 biological_processGO:0032880 regulation of protein localization IDA
 biological_processGO:0035459 cargo loading into vesicle IMP
 biological_processGO:0043547 positive regulation of GTPase activity IMP
 biological_processGO:0045056 transcytosis IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0048261 negative regulation of receptor-mediated endocytosis IDA
 biological_processGO:0048268 clathrin coat assembly IMP
 biological_processGO:0048813 dendrite morphogenesis IEA
 biological_processGO:0055072 iron ion homeostasis IMP
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0065003 protein-containing complex assembly TAS
 biological_processGO:0072583 clathrin-dependent endocytosis IMP
 biological_processGO:0090647 modulation of age-related behavioral decline ISS
 biological_processGO:0097494 regulation of vesicle size IMP
 biological_processGO:0097753 membrane bending IMP
 biological_processGO:0098711 iron ion import across plasma membrane IMP
 biological_processGO:1900223 positive regulation of amyloid-beta clearance ISS
 biological_processGO:1901216 positive regulation of neuron death IMP
 biological_processGO:1902003 regulation of amyloid-beta formation ISS
 biological_processGO:1902004 positive regulation of amyloid-beta formation TAS
 biological_processGO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process IMP
 biological_processGO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process ISS
 biological_processGO:1902963 negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process ISS
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane IMP
 biological_processGO:2000009 negative regulation of protein localization to cell surface IMP
 biological_processGO:2000370 positive regulation of clathrin-dependent endocytosis NAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005905 clathrin-coated pit ISS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030122 AP-2 adaptor complex IDA
 cellular_componentGO:0030132 clathrin coat of coated pit IDA
 cellular_componentGO:0030136 clathrin-coated vesicle IMP
 cellular_componentGO:0031224 intrinsic component of membrane ISS
 cellular_componentGO:0031982 vesicle ISS
 cellular_componentGO:0042734 presynaptic membrane ISS
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0045211 postsynaptic membrane ISS
 cellular_componentGO:0045334 clathrin-coated endocytic vesicle NAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 cellular_componentGO:0070381 endosome to plasma membrane transport vesicle IDA
 cellular_componentGO:0097418 neurofibrillary tangle IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005545 1-phosphatidylinositol binding ISS
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISS
 molecular_functionGO:0017137 Rab GTPase binding IPI
 molecular_functionGO:0030276 clathrin binding ISS
 molecular_functionGO:0032050 clathrin heavy chain binding IDA
 molecular_functionGO:0035615 clathrin adaptor activity IMP
 molecular_functionGO:0045296 cadherin binding HDA
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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