ENSDARG00000000729


Danio rerio

Features
Gene ID: ENSDARG00000000729
  
Biological name :daxx
  
Synonyms : daxx / death-domain associated protein
  
Possible biological names infered from orthology : Mus musculus Fas death domain-associated protein (Daxx), transcript variant 3, mRNA. / Q9UER7
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 7014455
Gene end: 7033670
  
Corresponding Affymetrix probe sets: Dr.21010.1.S1_at (Zebrafish Array)   Dr.8661.1.A1_at (Zebrafish Array)   NM_001044949_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000105452
Ensembl peptide - ENSDARP00000108588
Ensembl peptide - ENSDARP00000111223
NCBI entrez gene - 561006     See in Manteia.
RefSeq - NM_001044949
RefSeq Peptide - NP_001038414
swissprot - F1QQQ8
swissprot - E7F336
swissprot - Q1LUU4
ZFIN ID - ZDB-GENE-010110-3
Ensembl - ENSDARG00000000729
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DAXXENSG00000204209Homo sapiens
 DaxxENSMUSG00000002307Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005012  Daxx protein
 IPR031333  Daxx, N-terminal Rassf1C-interacting domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0003714 transcription corepressor activity IDA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors
Regulation of TP53 Degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / complex / reaction
 ENSDARG00000073710 usp7 / ubiquitin specific peptidase 7 (herpes virus-associated) / Q93009* / ubiquitin specific peptidase 7*  / reaction / complex
 ENSDARG00000033443 mdm2 / MDM2 oncogene, E3 ubiquitin protein ligase / P23804* / Q00987* / MDM2 proto-oncogene* / E3 ubiquitin-protein ligase Mdm2 *  / reaction / complex
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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