ENSDARG00000001873


Danio rerio

Features
Gene ID: ENSDARG00000001873
  
Biological name :phgdh
  
Synonyms : phgdh / phosphoglycerate dehydrogenase
  
Possible biological names infered from orthology : D-3-phosphoglycerate dehydrogenase / O43175 / Q61753
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 48185936
Gene end: 48214216
  
Corresponding Affymetrix probe sets: Dr.24995.5.A1_at (Zebrafish Array)   NM_199577_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000020860
NCBI entrez gene - 321928     See in Manteia.
RefSeq - NM_199577
RefSeq Peptide - NP_955871
swissprot - F1QEY8
ZFIN ID - ZDB-GENE-030131-647
Ensembl - ENSDARG00000001873
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PHGDHENSGALG00000002988Gallus gallus
 PHGDHENSG00000092621Homo sapiens
 PhgdhENSMUSG00000053398Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ctbp1 / C-terminal binding protein 1ENSDARG0000005700720
ctbp2a / C-terminal binding protein 2a / CTBP2* / P56545* / P56546* / C-terminal binding protein 2*ENSDARG0000004406220
zgc:136929 / CTBP1* / O88712* / Q13363* / C-terminal binding protein 1*ENSDARG0000001921319


Protein motifs (from Interpro)
Interpro ID Name
 IPR006139  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
 IPR006140  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
 IPR006236  D-3-phosphoglycerate dehydrogenase
 IPR016040  NAD(P)-binding domain
 IPR029009  Allosteric substrate binding domain superfamily
 IPR029752  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006564 L-serine biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008652 cellular amino acid biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004617 phosphoglycerate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Serine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000001873 phgdh / phosphoglycerate dehydrogenase / O43175* / Q61753* / D-3-phosphoglycerate dehydrogenase *  / complex






 

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