ENSGALG00000002988


Gallus gallus

Features
Gene ID: ENSGALG00000002988
  
Biological name :PHGDH
  
Synonyms : PHGDH / phosphoglycerate dehydrogenase
  
Possible biological names infered from orthology : D-3-phosphoglycerate dehydrogenase / O43175 / Q61753
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 4264703
Gene end: 4268005
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000004720
Ensembl peptide - ENSGALP00000062453
Ensembl peptide - ENSGALP00000051351
NCBI entrez gene - 424381     See in Manteia.
RefSeq - XM_422226
swissprot - E1C7Y3
swissprot - A0A1L1RUF5
swissprot - A0A1D5PEY9
Ensembl - ENSGALG00000002988
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phgdhENSDARG00000001873Danio rerio
 PHGDHENSG00000092621Homo sapiens
 PhgdhENSMUSG00000053398Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTBPLENSGALG0000000764222
CTBP1 / C-terminal-binding protein 1 / O88712* / Q13363*ENSGALG0000003994222
CTBP2 / C-terminal binding protein 2 / P56545* / P56546*ENSGALG0000000973821


Protein motifs (from Interpro)
Interpro ID Name
 IPR006139  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
 IPR006140  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
 IPR006236  D-3-phosphoglycerate dehydrogenase
 IPR016040  NAD(P)-binding domain
 IPR029009  Allosteric substrate binding domain superfamily
 IPR029752  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1
 IPR029753  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006541 glutamine metabolic process IEA
 biological_processGO:0006544 glycine metabolic process IEA
 biological_processGO:0006563 L-serine metabolic process IEA
 biological_processGO:0006564 L-serine biosynthetic process IEA
 biological_processGO:0006566 threonine metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008652 cellular amino acid biosynthetic process IEA
 biological_processGO:0009448 gamma-aminobutyric acid metabolic process IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0019530 taurine metabolic process IEA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0021782 glial cell development IEA
 biological_processGO:0021915 neural tube development IEA
 biological_processGO:0022008 neurogenesis IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070314 G1 to G0 transition IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0004617 phosphoglycerate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Serine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002988 PHGDH / phosphoglycerate dehydrogenase / O43175* / Q61753* / D-3-phosphoglycerate dehydrogenase *  / complex






 

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