ENSDARG00000002787


Danio rerio

Features
Gene ID: ENSDARG00000002787
  
Biological name :tle3a
  
Synonyms : tle3a / transducin-like enhancer of split 3a
  
Possible biological names infered from orthology : Q04726 / Q08122 / TLE3 / transducin like enhancer of split 3
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 20225961
Gene end: 20257511
  
Corresponding Affymetrix probe sets: Dr.659.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000045678
Ensembl peptide - ENSDARP00000091405
NCBI entrez gene - 30206     See in Manteia.
swissprot - E7F3V0
swissprot - Q1LXH1
ZFIN ID - ZDB-GENE-990415-86
Ensembl - ENSDARG00000002787
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TLE3ENSGALG00000008120Gallus gallus
 TLE3ENSG00000140332Homo sapiens
 Tle3ENSMUSG00000032280Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tle3b / O13168 / transducin-like enhancer of split 3b / TLE3* / Q08122* / Q04726* / transducin like enhancer of split 3*ENSDARG0000006900693
tle2a / transducin like enhancer of split 2aENSDARG0000004248472
tle2b / transducin like enhancer of split 2bENSDARG0000000876770
tle2c / transducin like enhancer of split 2cENSDARG0000006783220
chico / AES* / Q08117* / amino-terminal enhancer of split*ENSDARG0000001958816
aes / amino-terminal enhancer of split / P63002* / Q08117*ENSDARG0000002180515


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR005617  Groucho/TLE, N-terminal Q-rich domain
 IPR009146  Groucho/transducin-like enhancer
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA


Pathways (from Reactome)
Pathway description
Formation of the beta-catenin:TCF transactivating complex
Deactivation of the beta-catenin transactivating complex
Repression of WNT target genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000152 retina retina immature , abnormal
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 ZFA:0001080 sclerotome sclerotome structure , abnormal
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 ZFA:0001135 neural tube neural tube morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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