ENSDARG00000003259


Danio rerio

Features
Gene ID: ENSDARG00000003259
  
Biological name :loxa
  
Synonyms : loxa / lysyl oxidase a
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 7738540
Gene end: 7756876
  
Corresponding Affymetrix probe sets: Dr.11427.1.S1_at (Zebrafish Array)   NM_207089_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000014541
Ensembl peptide - ENSDARP00000102256
Ensembl peptide - ENSDARP00000110708
NCBI entrez gene - 404621     See in Manteia.
RefSeq - NM_207089
RefSeq - XM_005155442
RefSeq Peptide - NP_996972
swissprot - Q6NYT8
swissprot - F1QXL0
ZFIN ID - ZDB-GENE-040426-2398
Ensembl - ENSDARG00000003259
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
loxl5b / lysyl oxidase-like 5bENSDARG0000007690449
loxl5a / lysyl oxidase-like 5aENSDARG0000007168048
loxl1 / lysyl oxidase-like 1 / Q08397*ENSDARG0000005445148
loxl4 / lysyl oxidase-like 4ENSDARG0000002508934
F1QQC3 / loxl2a / lysyl oxidase-like 2a / LOXL2* / Q9Y4K0* / lysyl oxidase like 2*ENSDARG0000004401034
loxl2b / A1L1V4 / lysyl oxidase-like 2b / LOXL2* / Q9Y4K0* / P58022* / lysyl oxidase like 2* / Lysyl oxidase homolog 2 *ENSDARG0000004407433
B8A4W9 / loxl3b / lysyl oxidase-like 3bENSDARG0000003956333
F1RD85 / loxl3a / lysyl oxidase-like 3aENSDARG0000007630632
si:cabz01100188.1ENSDARG0000010544213
si:dkey-21h14.3ENSDARG0000009604710
si:dkey-242e21.3 / CD6* / P30203* / Q61003* / CD6 molecule* / T-cell differentiation antigen CD6 *ENSDARG000000757239
si:ch211-150o23.3ENSDARG000000785029
scara5 / Q5RFW0 / scavenger receptor class A, member 5 (putative) / Q8K299* / Q6ZMJ2* / scavenger receptor class A member 5*ENSDARG000000104252
marco / macrophage receptor with collagenous structure / Q9UEW3*ENSDARG000000592942
CT583642.2ENSDARG000001113151


Protein motifs (from Interpro)
Interpro ID Name
 IPR001695  Lysyl oxidase
 IPR013783  Immunoglobulin-like fold
 IPR019828  Lysyl oxidase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007517 muscle organ development IMP
 biological_processGO:0022008 neurogenesis IMP
 biological_processGO:0051216 cartilage development IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain structure , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000075 spinal cord spinal cord neuron disorganized , abnormal
spinal cord neuron decreased amount , abnormal
Show

 ZFA:0000107 eye eye colorless , abnormal
eye decreased size , abnormal
Show

 ZFA:0000135 notochord notochord morphology , abnormal
notochord undulate , abnormal
Show

 ZFA:0000155 somite somite shape , abnormal
somite condensed , abnormal
Show

 ZFA:0001094 whole organism whole organism morphology , abnormal
whole organism decreased length , abnormal
whole organism lethal (sensu genetics) , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curvature , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage deformed , abnormal
Show

 ZFA:0009090 pigment cell pigment cell spatial pattern , abnormal
Show

 ZFA:0009114 muscle cell muscle cell myofibril disorganized , abnormal
muscle cell myofibril decreased amount , abnormal
Show

 ZFA:0009244 primary motor neuron primary motor neuron axon decreased length , abnormal
primary motor neuron neuron projection decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr