ENSDARG00000044074


Danio rerio

Features
Gene ID: ENSDARG00000044074
  
Biological name :loxl2b
  
Synonyms : A1L1V4 / loxl2b / lysyl oxidase-like 2b
  
Possible biological names infered from orthology : LOXL2 / Lysyl oxidase homolog 2 / lysyl oxidase like 2 / P58022 / Q9Y4K0
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 27434601
Gene end: 27490499
  
Corresponding Affymetrix probe sets: Dr.23096.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000118755
Ensembl peptide - ENSDARP00000064700
Ensembl peptide - ENSDARP00000146651
Ensembl peptide - ENSDARP00000157626
NCBI entrez gene - 791144     See in Manteia.
swissprot - A1L1V4
ZFIN ID - ZDB-GENE-050208-29
Ensembl - ENSDARG00000044074
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000038458Gallus gallus
 LOXL2ENSG00000134013Homo sapiens
 Loxl2ENSMUSG00000034205Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
F1QQC3 / loxl2a / lysyl oxidase-like 2a / LOXL2* / Q9Y4K0* / lysyl oxidase like 2*ENSDARG0000004401070
B8A4W9 / loxl3b / lysyl oxidase-like 3bENSDARG0000003956356
F1RD85 / loxl3a / lysyl oxidase-like 3aENSDARG0000007630654
loxl4 / lysyl oxidase-like 4ENSDARG0000002508950
si:cabz01100188.1ENSDARG0000010544224
loxl1 / lysyl oxidase-like 1 / Q08397*ENSDARG0000005445120
loxa / lysyl oxidase aENSDARG0000000325918
loxl5b / lysyl oxidase-like 5bENSDARG0000007690417
loxl5a / lysyl oxidase-like 5aENSDARG0000007168016
si:ch211-150o23.3ENSDARG0000007850211
si:dkey-21h14.3ENSDARG0000009604711
si:dkey-242e21.3 / CD6* / P30203* / Q61003* / CD6 molecule* / T-cell differentiation antigen CD6 *ENSDARG0000007572311
scara5 / Q5RFW0 / scavenger receptor class A, member 5 (putative) / Q8K299* / Q6ZMJ2* / scavenger receptor class A member 5*ENSDARG0000001042510
marco / macrophage receptor with collagenous structure / Q9UEW3*ENSDARG000000592949
CT583642.2ENSDARG000001113156


Protein motifs (from Interpro)
Interpro ID Name
 IPR001190  SRCR domain
 IPR001695  Lysyl oxidase
 IPR013783  Immunoglobulin-like fold
 IPR017448  SRCR-like domain
 IPR019828  Lysyl oxidase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0001666 response to hypoxia ISS
 biological_processGO:0001837 epithelial to mesenchymal transition ISS
 biological_processGO:0001935 endothelial cell proliferation ISS
 biological_processGO:0002040 sprouting angiogenesis ISS
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition ISS
 biological_processGO:0018057 peptidyl-lysine oxidation ISS
 biological_processGO:0030199 collagen fibril organization ISS
 biological_processGO:0032332 positive regulation of chondrocyte differentiation ISS
 biological_processGO:0043542 endothelial cell migration ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070828 heterochromatin organization ISS
 biological_processGO:1902455 negative regulation of stem cell population maintenance ISS
 cellular_componentGO:0000785 chromatin ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005604 basement membrane ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004720 protein-lysine 6-oxidase activity ISS
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Crosslinking of collagen fibrils


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord kinked , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr