ENSDARG00000004587


Danio rerio

Features
Gene ID: ENSDARG00000004587
  
Biological name :kat5b
  
Synonyms : kat5a / kat5b / K(lysine) acetyltransferase 5b
  
Possible biological names infered from orthology : Histone acetyltransferase KAT5 / KAT5 / lysine acetyltransferase 5 / Q8CHK4 / Q92993
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 23597140
Gene end: 23605948
  
Corresponding Affymetrix probe sets: Dr.10302.1.A1_at (Zebrafish Array)   NM_001002365_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000030282
Ensembl peptide - ENSDARP00000113020
Ensembl peptide - ENSDARP00000118486
Ensembl peptide - ENSDARP00000121757
Ensembl peptide - ENSDARP00000123032
NCBI entrez gene - 436638     See in Manteia.
RefSeq - XM_005165139
RefSeq - NM_001002365
RefSeq Peptide - NP_001002365
swissprot - F6NPZ8
swissprot - B0R0X6
swissprot - B8JKI8
swissprot - F6NXN2
swissprot - F6PBI2
swissprot - Q6DHD0
ZFIN ID - ZDB-GENE-030131-985
ZFIN ID - ZDB-GENE-040718-57
Ensembl - ENSDARG00000004587
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KAT5ENSG00000172977Homo sapiens
 Kat5ENSMUSG00000024926Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kat5b / K(lysine) acetyltransferase 5b / KAT5* / Q8CHK4* / Q92993* / lysine acetyltransferase 5* / Histone acetyltransferase KAT5 *ENSDARG0000004595191
kat6a / K(lysine) acetyltransferase 6A / Q92794* / lysine acetyltransferase 6A*ENSDARG0000001890732
kat8 / K(lysine) acetyltransferase 8 / Q9D1P2* / Q9H7Z6* / lysine acetyltransferase 8* / Histone acetyltransferase KAT8 *ENSDARG0000002718732
kat7b / K(lysine) acetyltransferase 7b / KAT7* / O95251* / Q5SVQ0* / lysine acetyltransferase 7* / K(lysine) acetyltransferase 7*ENSDARG0000003177031
kat6b / K(lysine) acetyltransferase 6B / Q8BRB7* / Q8WYB5* / lysine acetyltransferase 6B* / Histone acetyltransferase KAT6B *ENSDARG0000005542926


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR002717  Histone acetyltransferase domain, MYST-type
 IPR016181  Acyl-CoA N-acyltransferase
 IPR016197  Chromo-like domain superfamily
 IPR025995  RNA binding activity-knot of a chromodomain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0060215 primitive hemopoiesis IMP
 biological_processGO:0060319 primitive erythrocyte differentiation IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Formation of the beta-catenin:TCF transactivating complex
DNA Damage/Telomere Stress Induced Senescence
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Sensing of DNA Double Strand Breaks
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Resolution of D-loop Structures through Holliday Junction Intermediates
Nonhomologous End-Joining (NHEJ)
Homologous DNA Pairing and Strand Exchange
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009325 erythroid lineage cell erythroid lineage cell increased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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