ENSDARG00000027187


Danio rerio

Features
Gene ID: ENSDARG00000027187
  
Biological name :kat8
  
Synonyms : kat8 / K(lysine) acetyltransferase 8
  
Possible biological names infered from orthology : Histone acetyltransferase KAT8 / lysine acetyltransferase 8 / Q9D1P2 / Q9H7Z6
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 32681274
Gene end: 32689328
  
Corresponding Affymetrix probe sets: Dr.2966.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000122112
Ensembl peptide - ENSDARP00000141609
NCBI entrez gene - 100003790     See in Manteia.
RefSeq - NM_212742
RefSeq Peptide - NP_997907
swissprot - F1QX50
swissprot - A0A0R4IZD0
ZFIN ID - ZDB-GENE-030131-7510
Ensembl - ENSDARG00000027187
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KAT8ENSG00000103510Homo sapiens
 Kat8ENSMUSG00000030801Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kat5b / kat5a / K(lysine) acetyltransferase 5b / KAT5* / Q92993* / Q8CHK4* / lysine acetyltransferase 5* / Histone acetyltransferase KAT5 *ENSDARG0000000458735
kat7b / K(lysine) acetyltransferase 7b / KAT7* / O95251* / Q5SVQ0* / lysine acetyltransferase 7* / K(lysine) acetyltransferase 7*ENSDARG0000003177035
kat6a / K(lysine) acetyltransferase 6A / Q92794* / lysine acetyltransferase 6A*ENSDARG0000001890735
kat5b / K(lysine) acetyltransferase 5b / KAT5* / Q8CHK4* / Q92993* / lysine acetyltransferase 5* / Histone acetyltransferase KAT5 *ENSDARG0000004595134
kat6b / K(lysine) acetyltransferase 6B / Q8BRB7* / Q8WYB5* / lysine acetyltransferase 6B* / Histone acetyltransferase KAT6B *ENSDARG0000005542929


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR002717  Histone acetyltransferase domain, MYST-type
 IPR016181  Acyl-CoA N-acyltransferase
 IPR016197  Chromo-like domain superfamily
 IPR025995  RNA binding activity-knot of a chromodomain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0060215 primitive hemopoiesis IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0072487 MSL complex IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009325 erythroid lineage cell erythroid lineage cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000038909 msl2a / male-specific lethal 2 homolog a (Drosophila) / MSL2* / Q9HCI7* / Q69ZF8* / MSL complex subunit 2* / E3 ubiquitin-protein ligase MSL2 *  / complex
 ENSDARG00000039430 msl2b / male-specific lethal 2 homolog b (Drosophila) / MSL2* / Q9HCI7* / Q69ZF8* / MSL complex subunit 2* / E3 ubiquitin-protein ligase MSL2 *  / complex
 ENSDARG00000090223 msl1b / male-specific lethal 1 homolog b (Drosophila) / MSL1* / Q68DK7* / Q6PDM1* / male specific lethal 1 homolog*  / complex






 

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