ENSDARG00000004753


Danio rerio

Features
Gene ID: ENSDARG00000004753
  
Biological name :mylkb
  
Synonyms : mylkb / myosin light chain kinase b
  
Possible biological names infered from orthology : MYLK / myosin light chain kinase / Q15746
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 13458257
Gene end: 13498745
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000019103
Ensembl peptide - ENSDARP00000154404
Ensembl peptide - ENSDARP00000139923
NCBI entrez gene - 492576     See in Manteia.
RefSeq - XM_009302263
swissprot - E7FDK2
swissprot - A0A0R4IWR6
ZFIN ID - ZDB-GENE-041111-150
Ensembl - ENSDARG00000004753
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYLKENSGALG00000011708Gallus gallus
 MYLKENSG00000065534Homo sapiens
 MylkENSMUSG00000022836Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mylka / myosin, light chain kinase a / MYLK* / Q15746* / myosin light chain kinase*ENSDARG0000003480165
mylk5 / myosin, light chain kinase 5ENSDARG0000007516434
spegb / SPEG complex locus b / SPEG* / Q62407* / Q15772* / SPEG complex locus*ENSDARG0000000956721
spega / SPEG complex locus a / SPEG* / Q15772* / SPEG complex locus*ENSDARG0000003925621
mylk3 / myosin light chain kinase 3 / Q32MK0* / Q3UIZ8*ENSDARG0000007634818
obscna / obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF aENSDARG0000004330918
mylk4b / myosin light chain kinase family, member 4b / MYLK4* / Q86YV6* / myosin light chain kinase family member 4*ENSDARG0000005541217
dapk1 / death-associated protein kinase 1 / P53355* / Q80YE7*ENSDARG0000006009316
mylk2 / myosin light chain kinase 2 / Q8VCR8* / Q9H1R3* / Myosin light chain kinase 2, skeletal/cardiac muscle *ENSDARG0000003169816
dapk2a / death-associated protein kinase 2a / DAPK2* / Q8VDF3* / Q9UIK4* / death associated protein kinase 2*ENSDARG0000006109615
dapk3 / death-associated protein kinase 3 / O43293* / O54784*ENSDARG0000007444714
dapk2b / death-associated protein kinase 2b / DAPK2* / Q9UIK4* / death associated protein kinase 2*ENSDARG0000010366613
si:dkey-240h12.4ENSDARG0000003421013
stk17b / serine/threonine kinase 17b (apoptosis-inducing) / O94768* / Q8BG48* / serine/threonine kinase 17b* / Serine/threonine-protein kinase 17B *ENSDARG0000001434812
stk17a / serine/threonine kinase 17a / Q9UEE5*ENSDARG0000007471512
stk17al / serine/threonine kinase 17a likeENSDARG0000001592212
mylk4a / myosin light chain kinase family, member 4a / MYLK4* / Q86YV6* / myosin light chain kinase family member 4*ENSDARG0000009126012


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Smooth Muscle Contraction
RHO GTPases activate PAKs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000100825 calm2a / calm2b / calm3a / Q6PI52 / calmodulin 2a (phosphorylase kinase, delta)  / reaction / complex






 

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