ENSDARG00000034801


Danio rerio

Features
Gene ID: ENSDARG00000034801
  
Biological name :mylka
  
Synonyms : mylka / myosin, light chain kinase a
  
Possible biological names infered from orthology : MYLK / myosin light chain kinase / Q15746
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 4024250
Gene end: 4075620
  
Corresponding Affymetrix probe sets: Dr.12326.1.A1_s_at (Zebrafish Array)   Dr.7877.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000046902
swissprot - F1R221
ZFIN ID - ZDB-GENE-030131-8207
Ensembl - ENSDARG00000034801
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYLKENSGALG00000011708Gallus gallus
 MYLKENSG00000065534Homo sapiens
 MylkENSMUSG00000022836Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mylkb / myosin light chain kinase b / MYLK* / Q15746* / myosin light chain kinase*ENSDARG0000000475370
mylk5 / myosin, light chain kinase 5ENSDARG0000007516436
spegb / SPEG complex locus b / SPEG* / Q62407* / Q15772* / SPEG complex locus*ENSDARG0000000956724
spega / SPEG complex locus a / SPEG* / Q15772* / SPEG complex locus*ENSDARG0000003925623
obscna / obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF aENSDARG0000004330919
mylk4b / myosin light chain kinase family, member 4b / MYLK4* / Q86YV6* / myosin light chain kinase family member 4*ENSDARG0000005541219
mylk3 / myosin light chain kinase 3 / Q32MK0* / Q3UIZ8*ENSDARG0000007634819
dapk1 / death-associated protein kinase 1 / P53355* / Q80YE7*ENSDARG0000006009318
mylk2 / myosin light chain kinase 2 / Q8VCR8* / Q9H1R3* / Myosin light chain kinase 2, skeletal/cardiac muscle *ENSDARG0000003169817
dapk2a / death-associated protein kinase 2a / DAPK2* / Q8VDF3* / Q9UIK4* / death associated protein kinase 2*ENSDARG0000006109616
dapk3 / death-associated protein kinase 3 / O43293* / O54784*ENSDARG0000007444716
si:dkey-240h12.4ENSDARG0000003421015
dapk2b / death-associated protein kinase 2b / DAPK2* / Q9UIK4* / death associated protein kinase 2*ENSDARG0000010366614
stk17b / serine/threonine kinase 17b (apoptosis-inducing) / O94768* / Q8BG48* / serine/threonine kinase 17b* / Serine/threonine-protein kinase 17B *ENSDARG0000001434813
stk17a / serine/threonine kinase 17a / Q9UEE5*ENSDARG0000007471513
mylk4a / myosin light chain kinase family, member 4a / MYLK4* / Q86YV6* / myosin light chain kinase family member 4*ENSDARG0000009126013
stk17al / serine/threonine kinase 17a likeENSDARG0000001592213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR015725  Myosin Light Chain Kinase 1, Kinase domain
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007596 blood coagulation IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:2000145 regulation of cell motility IGI
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Smooth Muscle Contraction
RHO GTPases activate PAKs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009323 thrombocyte thrombocyte shape , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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