ENSDARG00000004785


Danio rerio

Features
Gene ID: ENSDARG00000004785
  
Biological name :cops2
  
Synonyms : COP9 signalosome subunit 2 / cops2 / Q6IQT4
  
Possible biological names infered from orthology : COP9 signalosome complex subunit 2 / P61201 / P61202
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 32366071
Gene end: 32381663
  
Corresponding Affymetrix probe sets: Dr.4561.2.A1_at (Zebrafish Array)   NM_001002055_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000120999
Ensembl peptide - ENSDARP00000012359
NCBI entrez gene - 415145     See in Manteia.
RefSeq - NM_001002055
RefSeq - XM_005163159
RefSeq Peptide - NP_001002055
swissprot - Q6IQT4
swissprot - E9QI69
ZFIN ID - ZDB-GENE-040625-15
Ensembl - ENSDARG00000004785
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COPS2ENSGALG00000000404Gallus gallus
 COPS2ENSG00000166200Homo sapiens
 Cops2ENSMUSG00000027206Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
F1QGH9 / psmd11b / proteasome 26S subunit, non-ATPase 11b / O00231* / Q8BG32* / PSMD11* / proteasome 26S subunit, non-ATPase 11* / 26S proteasome non-ATPase regulatory subunit 11 *ENSDARG0000000513421
F6P3G4 / psmd11a / proteasome 26S subunit, non-ATPase 11a / O00231* / Q8BG32* / PSMD11* / proteasome 26S subunit, non-ATPase 11* / 26S proteasome non-ATPase regulatory subunit 11 *ENSDARG0000006015021


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000338 protein deneddylation IBA
 biological_processGO:0022008 neurogenesis IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IBA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0008180 COP9 signalosome IEA
 molecular_functionGO:0003714 transcription corepressor activity IBA


Pathways (from Reactome)
Pathway description
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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