ENSDARG00000005368


Danio rerio

Features
Gene ID: ENSDARG00000005368
  
Biological name :mcamb
  
Synonyms : mcamb / melanoma cell adhesion molecule b
  
Possible biological names infered from orthology : Cell surface glycoprotein MUC18 / MCAM / melanoma cell adhesion molecule / P43121 / Q8R2Y2
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 23271862
Gene end: 23342752
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000018583
NCBI entrez gene - 338313     See in Manteia.
RefSeq - NM_001012367
RefSeq Peptide - NP_001012367
swissprot - F1QIU5
ZFIN ID - ZDB-GENE-030219-213
Ensembl - ENSDARG00000005368
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCAMENSGALG00000030027Gallus gallus
 MCAMENSG00000076706Homo sapiens
 McamENSMUSG00000032135Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mcama / melanoma cell adhesion molecule a / MCAM* / P43121* / Q8R2Y2* / melanoma cell adhesion molecule* / Cell surface glycoprotein MUC18 *ENSDARG0000008964339
bcam / basal cell adhesion molecule (Lutheran blood group) / P50895* / Q9R069* / Basal cell adhesion molecule *ENSDARG0000009019024
alcamb / activated leukocyte cell adhesion molecule b / ALCAM* / Q13740* / Q61490* / CD166 antigen * / activated leukocyte cell adhesion molecule*ENSDARG0000005853822
alcama / activated leukocyte cell adhesion molecule a / ALCAM* / Q13740* / Q61490* / CD166 antigen * / activated leukocyte cell adhesion molecule*ENSDARG0000002653119


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0031103 axon regeneration IMP
 biological_processGO:0060026 convergent extension IMP
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0060287 epithelial cilium movement involved in determination of left/right asymmetry IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium decreased length , abnormal
Kupffers vesicle shape , abnormal
Kupffers vesicle decreased size , abnormal
Kupffers vesicle unlumenized , abnormal
Kupffers vesicle lumenized , abnormal
Kupffers vesicle anatomical region decreased volume , abnormal
Kupffers vesicle tube formation decreased occurrence , abnormal
Kupffers vesicle anatomical space decreased volume , abnormal
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 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
anatomical structure increased amount , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000060 prechordal plate prechordal plate spatial pattern , abnormal
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 ZFA:0000075 spinal cord spinal cord decreased amount , abnormal
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 ZFA:0000121 lateral plate mesoderm lateral plate mesoderm spatial pattern , abnormal
lateral plate mesoderm right side spatial pattern , abnormal
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 ZFA:0000135 notochord notochord spatial pattern , abnormal
notochord increased width , abnormal
Show

 ZFA:0000155 somite somite morphology , abnormal
somite spatial pattern , abnormal
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 ZFA:0001094 whole organism whole organism lacks all parts of type parachordal vessel , abnormal
whole organism dorsal region increased amount , abnormal
whole organism dorsal region increased distribution , abnormal
whole organism ventral region increased amount , abnormal
whole organism ventral region increased distribution , abnormal
whole organism decreased mobility , abnormal
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 ZFA:0001120 neuroectoderm neuroectoderm spatial pattern , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel aplastic , abnormal
intersegmental vessel decreased length , abnormal
intersegmental vessel hypoplastic , abnormal
intersegmental vessel decreased amount , abnormal
intersegmental vessel endothelial cell decreased amount , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel aplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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