ENSDARG00000006219


Danio rerio

Features
Gene ID: ENSDARG00000006219
  
Biological name :gnl3
  
Synonyms : gnl3 / guanine nucleotide binding protein-like 3 (nucleolar)
  
Possible biological names infered from orthology : G protein nucleolar 3 / Q8CI11 / Q9BVP2
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 3959495
Gene end: 3971035
  
Corresponding Affymetrix probe sets: Dr.7311.1.S1_at (Zebrafish Array)   NM_001002297_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000109517
NCBI entrez gene - 321897     See in Manteia.
RefSeq - NM_001002297
RefSeq Peptide - NP_001002297
swissprot - F1QGN5
ZFIN ID - ZDB-GENE-030131-616
Ensembl - ENSDARG00000006219
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GNL3ENSGALG00000001613Gallus gallus
 GNL3ENSG00000163938Homo sapiens
 Gnl3ENSMUSG00000042354Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gnl3l / guanine nucleotide binding protein-like 3 (nucleolar)-like / Q9NVN8* / G protein nucleolar 3 like*ENSDARG0000002059533


Protein motifs (from Interpro)
Interpro ID Name
 IPR006073  GTP binding domain
 IPR014813  Guanine nucleotide-binding protein-like 3, N-terminal domain
 IPR023179  GTP-binding protein, orthogonal bundle domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030378  Circularly permuted (CP)-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000024 retinal ganglion cell layer retinal ganglion cell layer immature , abnormal
Show

 ZFA:0000029 hindbrain hindbrain anterior/posterior pattern specification disrupted , abnormal
hindbrain radial glial cell morphology , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary decreased thickness , abnormal
Show

 ZFA:0000046 retinal neural layer retinal neural layer poorly differentiated , abnormal
retinal neural layer central region proliferative , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000059 postoptic commissure postoptic commissure morphology , abnormal
postoptic commissure astrocyte mislocalised , abnormal
Show

 ZFA:0000075 spinal cord spinal cord lacks all parts of type ventricular zone radial glial cell, abnormal
Show

 ZFA:0000079 telencephalon telencephalon decreased size , abnormal
Show

 ZFA:0000084 yolk yolk circular , abnormal
yolk grey , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000109 forebrain forebrain commissural neuron axon guidance disrupted , abnormal
forebrain decreased size , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle hydrocephalic , abnormal
fourth ventricle increased volume , abnormal
Show

 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
Show

 ZFA:0000114 heart heart quality , abnormal
Show

 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer immature , abnormal
Show

 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
Show

 ZFA:0000368 integument integument discolored , abnormal
integument rough , abnormal
Show

 ZFA:0000435 cranial nerve II cranial nerve II decreased size , abnormal
cranial nerve II decreased thickness , abnormal
Show

 ZFA:0000445 optic tectum optic tectum apoptotic , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism large ribosomal subunit decreased amount , abnormal
whole organism cytosolic ribosome decreased amount , abnormal
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 ZFA:0001108 anterior commissure anterior commissure morphology , abnormal
anterior commissure astrocyte mislocalised , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head apoptotic , abnormal
Show

 ZFA:0001117 post-vent region post-vent region apoptotic , abnormal
Show

 ZFA:0001259 forebrain ventricle forebrain ventricle increased volume , abnormal
Show

 ZFA:0001278 posterior chamber swim bladder posterior chamber swim bladder uninflated , abnormal
Show

 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer immature , abnormal
Show

 ZFA:0009255 amacrine cell amacrine cell decreased amount , abnormal
Show

 ZFA:0009292 radial glial cell radial glial cell cell projection disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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