Manteia

ENSDARG00000006220

Danio rerio

Features

Gene ID:	ENSDARG00000006220

Biological name :	ugt1ab

Synonyms :	UDP glucuronosyltransferase 1 family a, b / ugt1a1 / ugt1a2 / ugt1a6 / ugt1ab

Possible biological names infered from orthology :	P19224 / P22309 / P22310 / P35503 / P35504 / P70691 / Q62452 / Q63886 / Q64435 / Q6ZQM8 / Q9HAW7 / Q9HAW8 / Q9HAW9 / UDP glucuronosyltransferase 1 family, polypeptide A1 / UDP glucuronosyltransferase 1 family, polypeptide A2 / UDP glucuronosyltransferase 1 family, polypeptide A5 / UDP glucuronosyltransferase 1 family, polypeptide A6A / UDP glucuronosyltransferase 1 family, polypeptide A6B / UDP glucuronosyltransferase 1 family, polypeptide A7C / UDP glucuronosyltransferase 1 family, polypeptide A8 / UDP glucuronosyltransferase 1 family, polypeptide A9 / UDP glucuronosyltransferase family 1 member A1 / UDP glucuronosyltransferase family 1 member A10 / UDP glucuronosyltransferase family 1 member A3 / UDP glucuronosyltransferase family 1 member A4 / UDP glucuronosyltransferase family 1 member A5 / UDP glucuronosyltransferase family 1 member A6 / UDP glucuronosyltransferase family 1 member A7 / UDP glucuronosyltransferase family 1 member A8 / UDP glycosyltransferase 1 family, polypeptide A10 / UGT1A10 / UGT1A3 / UGT1A4 / UGT1A5 / Ugt1a6a / Ugt1a6b / UGT1A7 / Ugt1a7c / UGT1A8 / Ugt1a9

Species:	Danio rerio

Chr. number:	9
Strand:	-1
Band:
Gene start:	9969987
Gene end:	10003782

Corresponding Affymetrix probe sets:	Dr.3029.1.A1_at (Zebrafish Array) NM_001037428_at (Zebrafish Genome Array with custom cdf files) NM_213422_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000019395 Ensembl peptide - ENSDARP00000075904 Ensembl peptide - ENSDARP00000093225 Ensembl peptide - ENSDARP00000104687 Ensembl peptide - ENSDARP00000106286 Ensembl peptide - ENSDARP00000106675 Ensembl peptide - ENSDARP00000107388 Ensembl peptide - ENSDARP00000108527 Ensembl peptide - ENSDARP00000156616 Ensembl peptide - ENSDARP00000156725 Ensembl peptide - ENSDARP00000157038 NCBI entrez gene - 100384896 See in Manteia. NCBI entrez gene - 100379286 See in Manteia. NCBI entrez gene - 100384901 See in Manteia. NCBI entrez gene - 406731 See in Manteia. NCBI entrez gene - 641488 See in Manteia. RefSeq - NM_001037428 RefSeq - NM_001177344 RefSeq - NM_213422 RefSeq Peptide - NP_001170815 RefSeq Peptide - NP_998587 RefSeq Peptide - NP_001032505 swissprot - F1QAF6 swissprot - E9QF86 swissprot - F1QL72 swissprot - F1QM88 swissprot - F1QRI1 swissprot - F1R1P2 swissprot - F1R251 swissprot - Q561S7 ZFIN ID - ZDB-GENE-040426-2762 ZFIN ID - ZDB-GENE-071004-4 ZFIN ID - ZDB-GENE-071004-5 ZFIN ID - ZDB-GENE-080227-5 Ensembl - ENSDARG00000006220

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
	ENSGALG00000004196	Gallus gallus
P19224	ENSG00000167165	Homo sapiens
P22309	ENSG00000241635	Homo sapiens
P22310	ENSG00000244474	Homo sapiens
P35503	ENSG00000243135	Homo sapiens
P35504	ENSG00000240224	Homo sapiens
Q9HAW7	ENSG00000244122	Homo sapiens
Q9HAW8	ENSG00000242515	Homo sapiens
Q9HAW9	ENSG00000242366	Homo sapiens
P70691	ENSMUSG00000090171	Mus musculus
Q62452	ENSMUSG00000090175	Mus musculus
Q63886	ENSMUSG00000089960	Mus musculus
Q64435	ENSMUSG00000054545	Mus musculus
Q64435	ENSMUSG00000090124	Mus musculus
Ugt1a10	ENSMUSG00000090165	Mus musculus
Ugt1a5	ENSMUSG00000089943	Mus musculus
Ugt1a6b	ENSMUSG00000090145	Mus musculus
Ugt1a8	ENSMUSG00000089675	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
ugt1b1 / UDP glucuronosyltransferase 1 family, polypeptide B1 / P22310* / P35503* / P35504* / P70691* / Q62452* / Q63886* / Q64435* / Q9HAW7* / Q9HAW8* / Q9HAW9* / Q6ZQM8* / P19224* / P2230...	ENSDARG00000097491	61
ugt1b7 / UDP glucuronosyltransferase 1 family, polypeptide B7 / P22310* / P35503* / P35504* / P70691* / Q62452* / Q63886* / Q64435* / Q9HAW7* / Q9HAW8* / Q9HAW9* / Q6ZQM8* / P19224* / P2230...	ENSDARG00000101176	56
ugt1b3 / UDP glucuronosyltransferase 1 family, polypeptide B3 / P22310* / P35503* / P35504* / P70691* / Q62452* / Q63886* / Q64435* / Q9HAW7* / Q9HAW8* / Q9HAW9* / Q6ZQM8* / P19224* / P2230...	ENSDARG00000097979	55
ugt1b4 / UDP glucuronosyltransferase 1 family, polypeptide B4 / P22310* / P35503* / P35504* / P70691* / Q62452* / Q63886* / Q64435* / Q9HAW7* / Q9HAW8* / Q9HAW9* / Q6ZQM8* / P19224* / P2230...	ENSDARG00000097024	54
ugt1b5 / UDP glucuronosyltransferase 1 family, polypeptide B5 / P22310* / P35503* / P35504* / P70691* / Q62452* / Q63886* / Q64435* / Q9HAW7* / Q9HAW8* / Q9HAW9* / Q6ZQM8* / P19224* / P2230...	ENSDARG00000089507	54
ugt1b2 / UDP glucuronosyltransferase 1 family, polypeptide B2 / P22310* / P35503* / P35504* / P70691* / Q62452* / Q63886* / Q64435* / Q9HAW7* / Q9HAW8* / Q9HAW9* / Q6ZQM8* / P19224* / P2230...	ENSDARG00000097231	54
ugt2a7 / UDP glucuronosyltransferase 2 family, polypeptide A7 / P06133* / P16662* / P36537* / P54855* / Q6UWM9* / Q9BY64* / Q9Y4X1* / UGT2B7* / O75310* / O75795* / UGT2A1* / UGT2A2* / UGT2A...	ENSDARG00000093043	41
ugt2b5 / UDP glucuronosyltransferase 2 family, polypeptide B5 / P06133* / P16662* / P36537* / P54855* / Q6UWM9* / Q9BY64* / Q9Y4X1* / UGT2B7* / O75310* / O75795* / UGT2A1* / UGT2A2* / UGT2A...	ENSDARG00000116986	40
si:ch73-334d15.1	ENSDARG00000061672	40
ugt2a7 / UDP glucuronosyltransferase 2 family, polypeptide A7 / O75795* / P06133* / P16662* / P36537* / P54855* / Q6PDD0* / Q6UWM9* / Q80X89* / Q8BWQ1* / Q9BY64* / Q9Y4X1* / UGT2B7* / Ugt2b...	ENSDARG00000091624	40
ugt5g1 / UDP glucuronosyltransferase 5 family, polypeptide G1	ENSDARG00000032862	39
ugt2a1 / ugt2a4 / UDP glucuronosyltransferase 2 family, polypeptide A4 / P16662* / P36537* / P54855* / Q6PDD0* / Q6UWM9* / Q80X89* / Q8BWQ1* / Q9BY64* / Q9Y4X1* / UGT2B7* / Ugt2b5* / UGT2B4...	ENSDARG00000051940	39
ugt2a5 / UDP glucuronosyltransferase 2 family, polypeptide A5 / O75795* / P06133* / P16662* / P36537* / P54855* / Q6PDD0* / Q6UWM9* / Q80X89* / Q8BWQ1* / Q9BY64* / Q9Y4X1* / UGT2B7* / Ugt2b...	ENSDARG00000011537	39
ugt2a6 / ugt2a5 / UDP glucuronosyltransferase 2 family, polypeptide A6 / P06133* / P16662* / P36537* / P54855* / Q6PDD0* / Q6UWM9* / Q80X89* / Q8BWQ1* / Q9BY64* / Q9Y4X1* / UGT2B7* / Ugt2b5...	ENSDARG00000039501	38
ugt5g2 / UDP glucuronosyltransferase 5 family, polypeptide G2	ENSDARG00000043901	38
ugt5a2 / UDP glucuronosyltransferase 5 family, polypeptide A2	ENSDARG00000093640	38
ugt5f1 / UDP glucuronosyltransferase 5 family, polypeptide F1	ENSDARG00000054835	38
ugt5a1 / UDP glucuronosyltransferase 5 family, polypeptide A1	ENSDARG00000016479	37
ugt5e1 / UDP glucuronosyltransferase 5 family, polypeptide E1	ENSDARG00000058048	37
ugt5b2 / ugt5b3 / UDP glucuronosyltransferase 5 family, polypeptide B3	ENSDARG00000101495	36

Protein motifs (from Interpro)

Interpro ID	Name
IPR002213	UDP-glucuronosyl/UDP-glucosyltransferase
IPR035595	UDP-glycosyltransferase family, conserved site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0008152	metabolic process	IEA
biological_process	GO:0052696	flavonoid glucuronidation	IBA
biological_process	GO:0052697	xenobiotic glucuronidation	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IBA
molecular_function	GO:0015020	glucuronosyltransferase activity	IDA
molecular_function	GO:0016740	transferase activity	IEA
molecular_function	GO:0016757	transferase activity, transferring glycosyl groups	IEA
molecular_function	GO:0016758	transferase activity, transferring hexosyl groups	IEA

Pathways (from Reactome)

Pathway description

Glucuronidation

Heme degradation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr