ENSG00000243135


Homo sapiens

Features
Gene ID: ENSG00000243135
  
Biological name :UGT1A3
  
Synonyms : P35503 / UDP glucuronosyltransferase family 1 member A3 / UGT1A3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.1
Gene start: 233729108
Gene end: 233773299
  
Corresponding Affymetrix probe sets: 204532_x_at (Human Genome U133 Plus 2.0 Array)   206094_x_at (Human Genome U133 Plus 2.0 Array)   207126_x_at (Human Genome U133 Plus 2.0 Array)   208596_s_at (Human Genome U133 Plus 2.0 Array)   215125_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418532
NCBI entrez gene - 54659     See in Manteia.
OMIM - 606428
RefSeq - NM_019093
RefSeq Peptide - NP_061966
swissprot - P35503
swissprot - Q5DT01
Ensembl - ENSG00000243135
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ugt1a1ENSDARG00000006220Danio rerio
 ugt1b1ENSDARG00000097491Danio rerio
 ugt1b2ENSDARG00000097231Danio rerio
 ugt1b3ENSDARG00000097979Danio rerio
 ugt1b4ENSDARG00000097024Danio rerio
 ugt1b5ENSDARG00000089507Danio rerio
 ugt1b7ENSDARG00000101176Danio rerio
 ENSGALG00000004196Gallus gallus
 P70691ENSMUSG00000090171Mus musculus
 Ugt1a5ENSMUSG00000089943Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P35504 / UGT1A5 / UDP glucuronosyltransferase family 1 member A5ENSG0000024022495
P22310 / UGT1A4 / UDP glucuronosyltransferase family 1 member A4ENSG0000024447493
P22309 / UGT1A1 / UDP glucuronosyltransferase family 1 member A1ENSG0000024163572
Q9HAW9 / UGT1A8 / UDP glucuronosyltransferase family 1 member A8ENSG0000024236668
Q9HAW7 / UGT1A7 / UDP glucuronosyltransferase family 1 member A7ENSG0000024412267
P19224 / UGT1A6 / UDP glucuronosyltransferase family 1 member A6ENSG0000016716567
Q9HAW8 / UGT1A10 / UDP glucuronosyltransferase family 1 member A10ENSG0000024251567
O75795 / UGT2B17 / UDP glucuronosyltransferase family 2 member B17ENSG0000019788843
O75310 / UGT2B11 / UDP glucuronosyltransferase family 2 member B11ENSG0000021375942
P36537 / UGT2B10 / UDP glucuronosyltransferase family 2 member B10ENSG0000010918142
P06133 / UGT2B4 / UDP glucuronosyltransferase family 2 member B4ENSG0000015609642
P54855 / UGT2B15 / UDP glucuronosyltransferase family 2 member B15ENSG0000019662042
Q9Y4X1 / UGT2A2 / UDP glucuronosyltransferase family 2 member A2ENSG0000027127142
Q9BY64 / UGT2B28 / UDP glucuronosyltransferase family 2 member B28ENSG0000013522641
P16662 / UGT2B7 / UDP glucuronosyltransferase family 2 member B7ENSG0000017123441
Q6UWM9 / UGT2A3 / UDP glucuronosyltransferase family 2 member A3ENSG0000013522040
Q9Y4X1 / UGT2A1 / UDP glucuronosyltransferase family 2 member A1 complex locusENSG0000017361036
UGT8 / Q16880 / UDP glycosyltransferase 8ENSG0000017460730
Q6NUS8 / UGT3A1 / UDP glycosyltransferase family 3 member A1ENSG0000014562629
Q3SY77 / UGT3A2 / UDP glycosyltransferase family 3 member A2ENSG0000016867128


Protein motifs (from Interpro)
Interpro ID Name
 IPR002213  UDP-glucuronosyl/UDP-glucosyltransferase
 IPR035595  UDP-glycosyltransferase family, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0042573 retinoic acid metabolic process IC
 biological_processGO:0052695 cellular glucuronidation IDA
 biological_processGO:0052696 flavonoid glucuronidation IDA
 biological_processGO:0052697 xenobiotic glucuronidation IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0001972 retinoic acid binding IDA
 molecular_functionGO:0015020 glucuronosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016758 transferase activity, transferring hexosyl groups IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
Glucuronidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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