ENSG00000244122


Homo sapiens

Features
Gene ID: ENSG00000244122
  
Biological name :UGT1A7
  
Synonyms : Q9HAW7 / UDP glucuronosyltransferase family 1 member A7 / UGT1A7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.1
Gene start: 233681938
Gene end: 233773299
  
Corresponding Affymetrix probe sets: 204532_x_at (Human Genome U133 Plus 2.0 Array)   206094_x_at (Human Genome U133 Plus 2.0 Array)   207126_x_at (Human Genome U133 Plus 2.0 Array)   208596_s_at (Human Genome U133 Plus 2.0 Array)   215125_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362525
Ensembl peptide - ENSP00000420181
NCBI entrez gene - 54577     See in Manteia.
OMIM - 606432
RefSeq - NM_019077
RefSeq Peptide - NP_061950
swissprot - Q9HAW7
swissprot - H0Y8D7
swissprot - Q5DSZ7
Ensembl - ENSG00000244122
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ugt1a1ENSDARG00000006220Danio rerio
 ugt1b1ENSDARG00000097491Danio rerio
 ugt1b2ENSDARG00000097231Danio rerio
 ugt1b3ENSDARG00000097979Danio rerio
 ugt1b4ENSDARG00000097024Danio rerio
 ugt1b5ENSDARG00000089507Danio rerio
 ugt1b7ENSDARG00000101176Danio rerio
 ENSGALG00000004196Gallus gallus
 Q62452ENSMUSG00000090175Mus musculus
 Ugt1a10ENSMUSG00000090165Mus musculus
 Ugt1a8ENSMUSG00000089675Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9HAW9 / UGT1A8 / UDP glucuronosyltransferase family 1 member A8ENSG0000024236695
Q9HAW8 / UGT1A10 / UDP glucuronosyltransferase family 1 member A10ENSG0000024251594
P35504 / UGT1A5 / UDP glucuronosyltransferase family 1 member A5ENSG0000024022468
P19224 / UGT1A6 / UDP glucuronosyltransferase family 1 member A6ENSG0000016716568
P22309 / UGT1A1 / UDP glucuronosyltransferase family 1 member A1ENSG0000024163567
P22310 / UGT1A4 / UDP glucuronosyltransferase family 1 member A4ENSG0000024447467
P35503 / UGT1A3 / UDP glucuronosyltransferase family 1 member A3ENSG0000024313567
P36537 / UGT2B10 / UDP glucuronosyltransferase family 2 member B10ENSG0000010918142
P54855 / UGT2B15 / UDP glucuronosyltransferase family 2 member B15ENSG0000019662042
P06133 / UGT2B4 / UDP glucuronosyltransferase family 2 member B4ENSG0000015609642
O75795 / UGT2B17 / UDP glucuronosyltransferase family 2 member B17ENSG0000019788842
Q9Y4X1 / UGT2A2 / UDP glucuronosyltransferase family 2 member A2ENSG0000027127141
Q6UWM9 / UGT2A3 / UDP glucuronosyltransferase family 2 member A3ENSG0000013522041
O75310 / UGT2B11 / UDP glucuronosyltransferase family 2 member B11ENSG0000021375941
P16662 / UGT2B7 / UDP glucuronosyltransferase family 2 member B7ENSG0000017123440
Q9BY64 / UGT2B28 / UDP glucuronosyltransferase family 2 member B28ENSG0000013522640
Q9Y4X1 / UGT2A1 / UDP glucuronosyltransferase family 2 member A1 complex locusENSG0000017361036
UGT8 / Q16880 / UDP glycosyltransferase 8ENSG0000017460732
Q3SY77 / UGT3A2 / UDP glycosyltransferase family 3 member A2ENSG0000016867127
Q6NUS8 / UGT3A1 / UDP glycosyltransferase family 3 member A1ENSG0000014562627


Protein motifs (from Interpro)
Interpro ID Name
 IPR002213  UDP-glucuronosyl/UDP-glucosyltransferase
 IPR035595  UDP-glycosyltransferase family, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007588 excretion IC
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009804 coumarin metabolic process IC
 biological_processGO:0017144 drug metabolic process IC
 biological_processGO:0042573 retinoic acid metabolic process IC
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0051552 flavone metabolic process IC
 biological_processGO:0052695 cellular glucuronidation IDA
 biological_processGO:0052696 flavonoid glucuronidation IDA
 biological_processGO:0052697 xenobiotic glucuronidation IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0001972 retinoic acid binding IDA
 molecular_functionGO:0004857 enzyme inhibitor activity IDA
 molecular_functionGO:0005080 protein kinase C binding IDA
 molecular_functionGO:0015020 glucuronosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016758 transferase activity, transferring hexosyl groups IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
Glucuronidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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