ENSG00000167165


Homo sapiens

Features
Gene ID: ENSG00000167165
  
Biological name :UGT1A6
  
Synonyms : P19224 / UDP glucuronosyltransferase family 1 member A6 / UGT1A6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.1
Gene start: 233691607
Gene end: 233773300
  
Corresponding Affymetrix probe sets: 204532_x_at (Human Genome U133 Plus 2.0 Array)   206094_x_at (Human Genome U133 Plus 2.0 Array)   207126_x_at (Human Genome U133 Plus 2.0 Array)   208596_s_at (Human Genome U133 Plus 2.0 Array)   215125_s_at (Human Genome U133 Plus 2.0 Array)   232654_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000386107
Ensembl peptide - ENSP00000419780
Ensembl peptide - ENSP00000401541
Ensembl peptide - ENSP00000389637
Ensembl peptide - ENSP00000303174
Ensembl peptide - ENSP00000362523
NCBI entrez gene - 54578     See in Manteia.
OMIM - 606431
RefSeq - NM_205862
RefSeq - NM_001072
RefSeq Peptide - NP_001063
RefSeq Peptide - NP_995584
swissprot - Q5DSZ8
swissprot - B5MCT4
swissprot - H7C5F8
swissprot - P19224
swissprot - C9JMY5
Ensembl - ENSG00000167165
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ugt1a1ENSDARG00000006220Danio rerio
 ugt1b1ENSDARG00000097491Danio rerio
 ugt1b2ENSDARG00000097231Danio rerio
 ugt1b3ENSDARG00000097979Danio rerio
 ugt1b4ENSDARG00000097024Danio rerio
 ugt1b5ENSDARG00000089507Danio rerio
 ugt1b7ENSDARG00000101176Danio rerio
 ENSGALG00000004196Gallus gallus
 Q64435ENSMUSG00000054545Mus musculus
 Q64435ENSMUSG00000090124Mus musculus
 Ugt1a6bENSMUSG00000090145Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P22309 / UGT1A1 / UDP glucuronosyltransferase family 1 member A1ENSG0000024163569
P22310 / UGT1A4 / UDP glucuronosyltransferase family 1 member A4ENSG0000024447468
Q9HAW9 / UGT1A8 / UDP glucuronosyltransferase family 1 member A8ENSG0000024236667
Q9HAW7 / UGT1A7 / UDP glucuronosyltransferase family 1 member A7ENSG0000024412267
P35504 / UGT1A5 / UDP glucuronosyltransferase family 1 member A5ENSG0000024022467
Q9HAW8 / UGT1A10 / UDP glucuronosyltransferase family 1 member A10ENSG0000024251567
P35503 / UGT1A3 / UDP glucuronosyltransferase family 1 member A3ENSG0000024313567
Q6UWM9 / UGT2A3 / UDP glucuronosyltransferase family 2 member A3ENSG0000013522042
P54855 / UGT2B15 / UDP glucuronosyltransferase family 2 member B15ENSG0000019662042
O75795 / UGT2B17 / UDP glucuronosyltransferase family 2 member B17ENSG0000019788842
P36537 / UGT2B10 / UDP glucuronosyltransferase family 2 member B10ENSG0000010918142
P06133 / UGT2B4 / UDP glucuronosyltransferase family 2 member B4ENSG0000015609641
Q9Y4X1 / UGT2A2 / UDP glucuronosyltransferase family 2 member A2ENSG0000027127141
O75310 / UGT2B11 / UDP glucuronosyltransferase family 2 member B11ENSG0000021375941
P16662 / UGT2B7 / UDP glucuronosyltransferase family 2 member B7ENSG0000017123440
Q9BY64 / UGT2B28 / UDP glucuronosyltransferase family 2 member B28ENSG0000013522640
Q9Y4X1 / UGT2A1 / UDP glucuronosyltransferase family 2 member A1 complex locusENSG0000017361037
UGT8 / Q16880 / UDP glycosyltransferase 8ENSG0000017460731
Q3SY77 / UGT3A2 / UDP glycosyltransferase family 3 member A2ENSG0000016867128
Q6NUS8 / UGT3A1 / UDP glycosyltransferase family 3 member A1ENSG0000014562627


Protein motifs (from Interpro)
Interpro ID Name
 IPR002213  UDP-glucuronosyl/UDP-glucosyltransferase
 IPR035595  UDP-glycosyltransferase family, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0052695 cellular glucuronidation TAS
 biological_processGO:0052696 flavonoid glucuronidation IBA
 biological_processGO:0052697 xenobiotic glucuronidation IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0015020 glucuronosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016758 transferase activity, transferring hexosyl groups IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
Glucuronidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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