ENSG00000174607


Homo sapiens

Features
Gene ID: ENSG00000174607
  
Biological name :UGT8
  
Synonyms : Q16880 / UDP glycosyltransferase 8 / UGT8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q26
Gene start: 114598455
Gene end: 114678224
  
Corresponding Affymetrix probe sets: 208358_s_at (Human Genome U133 Plus 2.0 Array)   228956_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421446
Ensembl peptide - ENSP00000311648
Ensembl peptide - ENSP00000378019
NCBI entrez gene - 7368     See in Manteia.
OMIM - 601291
RefSeq - NM_001322113
RefSeq - NM_001128174
RefSeq - NM_001322112
RefSeq - NM_001322114
RefSeq - NM_003360
RefSeq Peptide - NP_001309042
RefSeq Peptide - NP_001121646
RefSeq Peptide - NP_001309041
RefSeq Peptide - NP_001309043
RefSeq Peptide - NP_003351
swissprot - Q16880
swissprot - D6RFW2
Ensembl - ENSG00000174607
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ugt8ENSDARG00000037455Danio rerio
 UGT8ENSGALG00000012018Gallus gallus
 Ugt8aENSMUSG00000032854Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P54855 / UGT2B15 / UDP glucuronosyltransferase family 2 member B15ENSG0000019662033
O75795 / UGT2B17 / UDP glucuronosyltransferase family 2 member B17ENSG0000019788833
P06133 / UGT2B4 / UDP glucuronosyltransferase family 2 member B4ENSG0000015609632
Q6UWM9 / UGT2A3 / UDP glucuronosyltransferase family 2 member A3ENSG0000013522032
Q9Y4X1 / UGT2A2 / UDP glucuronosyltransferase family 2 member A2ENSG0000027127132
P16662 / UGT2B7 / UDP glucuronosyltransferase family 2 member B7ENSG0000017123431
P36537 / UGT2B10 / UDP glucuronosyltransferase family 2 member B10ENSG0000010918131
Q9HAW7 / UGT1A7 / UDP glucuronosyltransferase family 1 member A7ENSG0000024412231
Q9HAW8 / UGT1A10 / UDP glucuronosyltransferase family 1 member A10ENSG0000024251531
Q9HAW9 / UGT1A8 / UDP glucuronosyltransferase family 1 member A8ENSG0000024236631
O75310 / UGT2B11 / UDP glucuronosyltransferase family 2 member B11ENSG0000021375931
P35504 / UGT1A5 / UDP glucuronosyltransferase family 1 member A5ENSG0000024022430
P22310 / UGT1A4 / UDP glucuronosyltransferase family 1 member A4ENSG0000024447430
P19224 / UGT1A6 / UDP glucuronosyltransferase family 1 member A6ENSG0000016716530
Q9BY64 / UGT2B28 / UDP glucuronosyltransferase family 2 member B28ENSG0000013522630
P35503 / UGT1A3 / UDP glucuronosyltransferase family 1 member A3ENSG0000024313530
Q9Y4X1 / UGT2A1 / UDP glucuronosyltransferase family 2 member A1 complex locusENSG0000017361030
P22309 / UGT1A1 / UDP glucuronosyltransferase family 1 member A1ENSG0000024163530
Q6NUS8 / UGT3A1 / UDP glycosyltransferase family 3 member A1ENSG0000014562628
Q3SY77 / UGT3A2 / UDP glycosyltransferase family 3 member A2ENSG0000016867128


Protein motifs (from Interpro)
Interpro ID Name
 IPR002213  UDP-glucuronosyl/UDP-glucosyltransferase
 IPR035595  UDP-glycosyltransferase family, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002175 protein localization to paranode region of axon IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0006682 galactosylceramide biosynthetic process IEA
 biological_processGO:0006687 glycosphingolipid metabolic process TAS
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007417 central nervous system development TAS
 biological_processGO:0007422 peripheral nervous system development TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030913 paranodal junction assembly IEA
 biological_processGO:0048812 neuron projection morphogenesis IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 molecular_functionGO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity TAS
 molecular_functionGO:0015020 glucuronosyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016758 transferase activity, transferring hexosyl groups IEA
 molecular_functionGO:0047263 N-acylsphingosine galactosyltransferase activity TAS


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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