ENSDARG00000006677


Danio rerio

Features
Gene ID: ENSDARG00000006677
  
Biological name :ripk1l
  
Synonyms : receptor (TNFRSF)-interacting serine-threonine kinase 1, like / ripk1l
  
Possible biological names infered from orthology : Q13546 / Q60855 / receptor interacting serine/threonine kinase 1 / Receptor-interacting serine/threonine-protein kinase 1 / RIPK1
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 904362
Gene end: 920580
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000014604
NCBI entrez gene - 567460     See in Manteia.
RefSeq - NM_001043350
RefSeq Peptide - NP_001036815
swissprot - A8DZG7
ZFIN ID - ZDB-GENE-070705-132
Ensembl - ENSDARG00000006677
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RIPK1ENSGALG00000012827Gallus gallus
 RIPK1ENSG00000137275Homo sapiens
 Ripk1ENSMUSG00000021408Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ripk4 / receptor-interacting serine-threonine kinase 4 / P57078* / Q9ERK0* / Receptor-interacting serine/threonine-protein kinase 4 *ENSDARG0000004321118
ankk1 / ankyrin repeat and kinase domain containing 1 / Q8BZ25* / Q8NFD2* / Ankyrin repeat and protein kinase domain-containing protein 1 *ENSDARG0000005692116
ripk2 / receptor-interacting serine-threonine kinase 2 / O43353*ENSDARG0000010429013
adgrg1 / adhesion G protein-coupled receptor G1ENSDARG0000010564312
ripk3 / receptor-interacting serine-threonine kinase 3 / Q9Y572*ENSDARG0000009096511


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011029  Death-like domain superfamily
 IPR025735  RHIM domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Regulation by c-FLIP
RIPK1-mediated regulated necrosis
CASP8 activity is inhibited
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Ub-specific processing proteases
Ovarian tumor domain proteases
Dimerization of procaspase-8
TNF signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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