ENSDARG00000104290


Danio rerio

Features
Gene ID: ENSDARG00000104290
  
Biological name :ripk2
  
Synonyms : receptor-interacting serine-threonine kinase 2 / ripk2
  
Possible biological names infered from orthology : O43353 / P58801 / receptor (TNFRSF)-interacting serine-threonine kinase 2
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 7557912
Gene end: 7587660
  
Corresponding Affymetrix probe sets: DrAffx.1.29.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000134516
swissprot - A0A0R4IKJ5
ZFIN ID - ZDB-GENE-030902-3
Ensembl - ENSDARG00000104290
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RIPK2ENSGALG00000043535Gallus gallus
 RIPK2ENSG00000104312Homo sapiens
 Ripk2ENSMUSG00000041135Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ripk4 / receptor-interacting serine-threonine kinase 4 / P57078* / Q9ERK0* / Receptor-interacting serine/threonine-protein kinase 4 *ENSDARG0000004321126
ankk1 / ankyrin repeat and kinase domain containing 1 / Q8BZ25* / Q8NFD2* / Ankyrin repeat and protein kinase domain-containing protein 1 *ENSDARG0000005692122
adgrg1 / adhesion G protein-coupled receptor G1ENSDARG0000010564319
ripk1l / receptor (TNFRSF)-interacting serine-threonine kinase 1, like / RIPK1* / Q60855* / Q13546* / receptor interacting serine/threonine kinase 1* / Receptor-interacting serine/threonine...ENSDARG0000000667719
ripk3 / receptor-interacting serine-threonine kinase 3 / Q9Y572*ENSDARG0000009096516


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IGI
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0042742 defense response to bacterium IDA
 biological_processGO:0051607 defense response to virus IDA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0050700 CARD domain binding ISS


Pathways (from Reactome)
Pathway description
NOD1/2 Signaling Pathway
Downstream TCR signaling
p75NTR recruits signalling complexes
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Ovarian tumor domain proteases
Interleukin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr