ENSDARG00000007377


Danio rerio

Features
Gene ID: ENSDARG00000007377
  
Biological name :odc1
  
Synonyms : odc1 / ornithine decarboxylase 1
  
Possible biological names infered from orthology : ornithine decarboxylase, structural 1 / P00860 / P11926
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 51743908
Gene end: 51760243
  
Corresponding Affymetrix probe sets: Dr.5578.2.S1_a_at (Zebrafish Array)   NM_131801_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000123821
Ensembl peptide - ENSDARP00000124918
Ensembl peptide - ENSDARP00000150138
Ensembl peptide - ENSDARP00000154168
Ensembl peptide - ENSDARP00000124766
NCBI entrez gene - 114426     See in Manteia.
RefSeq - NM_131801
RefSeq Peptide - NP_571876
swissprot - F8W2D7
swissprot - F8W507
swissprot - Q9DGJ4
ZFIN ID - ZDB-GENE-010816-1
Ensembl - ENSDARG00000007377
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ODC1ENSGALG00000016444Gallus gallus
 ODC1ENSG00000115758Homo sapiens
 Odc1ENSMUSG00000011179Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
azin1b / antizyme inhibitor 1b / AZIN1* / O14977* / O35484* / antizyme inhibitor 1*ENSDARG0000003586939
azin1a / antizyme inhibitor 1a / AZIN1* / O14977* / O35484* / antizyme inhibitor 1*ENSDARG0000005278938


Protein motifs (from Interpro)
Interpro ID Name
 IPR000183  Ornithine/DAP/Arg decarboxylase
 IPR002433  Ornithine decarboxylase
 IPR009006  Alanine racemase/group IV decarboxylase, C-terminal
 IPR022643  Orn/DAP/Arg decarboxylase 2, C-terminal
 IPR022644  Orn/DAP/Arg decarboxylase 2, N-terminal
 IPR022653  Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site
 IPR022657  Orn/DAP/Arg decarboxylase 2, conserved site
 IPR029066  PLP-binding barrel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006596 polyamine biosynthetic process IEA
 biological_processGO:0033387 putrescine biosynthetic process from ornithine IBA
 biological_processGO:0042462 eye photoreceptor cell development IMP
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004586 ornithine decarboxylase activity IBA


Pathways (from Reactome)
Pathway description
Regulation of ornithine decarboxylase (ODC)
Metabolism of polyamines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
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 ZFA:0000123 liver liver hypoplastic , abnormal
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 ZFA:0000143 retinal photoreceptor layer retinal photoreceptor layer quality , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000059815 oaz2b / ornithine decarboxylase antizyme 2b / OAZ3* / Q9R109* / Q9UMX2* / ornithine decarboxylase antizyme 3* / Mus musculus ornithine decarboxylase antizyme 3 (Oaz3), mRNA.*  / complex / reaction
 ENSDARG00000071403 oaz1a / Q9YI98 / ornithine decarboxylase antizyme 1a / OAZ1* / P54368* / P54369* / ornithine decarboxylase antizyme 1* / Mus musculus ornithine decarboxylase antizyme 1 (Oaz1), transcript v...  / complex / reaction
 ENSDARG00000045929 oaz2a / ornithine decarboxylase antizyme 2a / OAZ2* / O95190* / O08608* / ornithine decarboxylase antizyme 2* / Mus musculus ornithine decarboxylase antizyme 2 (Oaz2), transcript variant 1, mRNA.*  / complex / reaction
 ENSDARG00000010250 nqo1 / NAD(P)H dehydrogenase, quinone 1 / P15559* / Q64669* / NAD(P)H quinone dehydrogenase 1*  / complex / reaction






 

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