ENSDARG00000008170


Danio rerio

Features
Gene ID: ENSDARG00000008170
  
Biological name :dbnla
  
Synonyms : dbnla / drebrin-like a
  
Possible biological names infered from orthology : DBNL / drebrin like / Drebrin-like protein / Q62418 / Q9UJU6
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 42358426
Gene end: 42372811
  
Corresponding Affymetrix probe sets: Dr.16116.1.S1_at (Zebrafish Array)   NM_001002201_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000026512
NCBI entrez gene - 431748     See in Manteia.
RefSeq - XM_009305664
RefSeq - NM_001002201
RefSeq Peptide - NP_001002201
swissprot - Q6GMH1
ZFIN ID - ZDB-GENE-040704-42
Ensembl - ENSDARG00000008170
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DBNLENSG00000136279Homo sapiens
 DbnlENSMUSG00000020476Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dbnlb / drebrin-like b / DBNL* / Q9UJU6* / drebrin like*ENSDARG0000001601652
si:dkey-40c11.2ENSDARG0000003248233
dbn1 / drebrin 1 / Q16643*ENSDARG0000006911328
hcls1 / hematopoietic cell-specific Lyn substrate 1 / P14317* / P49710* / Hematopoietic lineage cell-specific protein *ENSDARG0000001272917
cttn / cortactin / Q14247*ENSDARG0000001177717


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR002108  Actin-depolymerising factor homology domain
 IPR029006  ADF-H/Gelsolin-like domain superfamily
 IPR029923  Drebrin-like protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0007416 synapse assembly IEA
 biological_processGO:0048812 neuron projection morphogenesis IEA
 biological_processGO:0097178 ruffle assembly IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Caspase-mediated cleavage of cytoskeletal proteins
Neurexins and neuroligins
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000055459 dlgap3 / discs, large (Drosophila) homolog-associated protein 3 / O95886* / Q6PFD5* / DLG associated protein 3* / Disks large-associated protein 3 *  / complex / reaction
 ENSDARG00000062325 shank2 / SH3 and multiple ankyrin repeat domains 2 / Q80Z38* / Q9UPX8* / SH3 and multiple ankyrin repeat domains protein 2 *  / complex / reaction






 

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