ENSDARG00000008947


Danio rerio

Features
Gene ID: ENSDARG00000008947
  
Biological name :rtf1
  
Synonyms : rtf1 / RTF1 homolog, Paf1/RNA polymerase II complex component
  
Possible biological names infered from orthology : A2AQ19 / Q92541 / RNA polymerase-associated
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 33229446
Gene end: 33246154
  
Corresponding Affymetrix probe sets: Dr.15115.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000110578
NCBI entrez gene - 100000471     See in Manteia.
RefSeq - NM_001083577
RefSeq Peptide - NP_001077046
swissprot - G1K2X4
ZFIN ID - ZDB-GENE-030131-6778
Ensembl - ENSDARG00000008947
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RTF1ENSGALG00000008595Gallus gallus
 RTF1ENSG00000137815Homo sapiens
 Rtf1ENSMUSG00000027304Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004343  Plus-3 domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR031102  RNA polymerase-associated protein Rtf1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0016570 histone modification IEA
 biological_processGO:0036342 post-anal tail morphogenesis IGI
 biological_processGO:0043473 pigmentation IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0016593 Cdc73/Paf1 complex IBA
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:1990269 RNA polymerase II C-terminal domain phosphoserine binding IBA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000077 tail bud tail bud decreased size , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000217 inner ear inner ear decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism curved ventral , abnormal
Show

 ZFA:0001115 trunk trunk somite border disorganized , abnormal
Show

 ZFA:0005490 myocardial precursor myocardial precursor decreased amount , abnormal
Show

 ZFA:0009091 melanocyte melanocyte melanosome decreased pigmentation , abnormal
melanocyte decreased amount , abnormal
Show

 ZFA:0009165 neural crest cell neural crest cell decreased amount , abnormal
neural crest cell absent , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr