ENSMUSG00000027304


Mus musculus

Features
Gene ID: ENSMUSG00000027304
  
Biological name :Rtf1
  
Synonyms : A2AQ19 / RNA polymerase-associated / Rtf1
  
Possible biological names infered from orthology : Q92541 / RTF1 homolog, Paf1/RNA polymerase II complex component
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: E5
Gene start: 119675068
Gene end: 119735407
  
Corresponding Affymetrix probe sets: 10475000 (MoGene1.0st)   1429047_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028767
NCBI entrez gene - 76246     See in Manteia.
MGI - MGI:1309480
RefSeq - NM_030112
RefSeq - XM_017319319
RefSeq Peptide - NP_084388
swissprot - A2AQ19
Ensembl - ENSMUSG00000027304
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rtf1ENSDARG00000008947Danio rerio
 RTF1ENSGALG00000008595Gallus gallus
 RTF1ENSG00000137815Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004343  Plus-3 domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR031102  RNA polymerase-associated protein Rtf1
 IPR036128  Plus3-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0001711 endodermal cell fate commitment IMP
 biological_processGO:0001832 blastocyst growth IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016570 histone modification IEA
 biological_processGO:0019827 stem cell population maintenance IMP
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051571 positive regulation of histone H3-K4 methylation IMP
 biological_processGO:0080182 histone H3-K4 trimethylation IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0016593 Cdc73/Paf1 complex ISO
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:1990269 RNA polymerase II C-terminal domain phosphoserine binding IBA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Rad9atm1.1(KOMP)Wtsi/Rad9atm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad9atm1.1(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr