ENSDARG00000009942


Danio rerio

Features
Gene ID: ENSDARG00000009942
  
Biological name :cdc6
  
Synonyms : cdc6 / cell division cycle 6 homolog (S. cerevisiae)
  
Possible biological names infered from orthology : Cell division control / cell division cycle 6 / O89033 / Q99741
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 11781973
Gene end: 11792766
  
Corresponding Affymetrix probe sets: Dr.3850.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000008736
Ensembl peptide - ENSDARP00000148253
NCBI entrez gene - 402825     See in Manteia.
RefSeq - NM_001127333
RefSeq Peptide - NP_001120805
swissprot - F1R1N7
ZFIN ID - ZDB-GENE-050506-131
Ensembl - ENSDARG00000009942
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDC6ENSGALG00000036519Gallus gallus
 CDC6ENSG00000094804Homo sapiens
 Cdc6ENSMUSG00000017499Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
orc1 / origin recognition complex, subunit 1 / Q13415* / Q9Z1N2*ENSDARG0000003921722


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR011991  ArsR-like helix-turn-helix domain
 IPR015163  Cdc6, C-terminal
 IPR016314  Cell division protein Cdc6/18
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006270 DNA replication initiation IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex
CDK-mediated phosphorylation and removal of Cdc6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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