ENSGALG00000036519


Gallus gallus

Features
Gene ID: ENSGALG00000036519
  
Biological name :CDC6
  
Synonyms : CDC6 / cell division cycle 6
  
Possible biological names infered from orthology : Cell division control / O89033 / Q99741
  
Species: Gallus gallus
  
Chr. number: 27
Strand: 1
Band:
Gene start: 4823987
Gene end: 4828032
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000047442
Ensembl peptide - ENSGALP00000050313
swissprot - A0A1D5P436
swissprot - A0A1D5PC28
Ensembl - ENSGALG00000036519
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc6ENSDARG00000009942Danio rerio
 CDC6ENSG00000094804Homo sapiens
 Cdc6ENSMUSG00000017499Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ORC1 / origin recognition complex subunit 1 / Q13415* / Q9Z1N2*ENSGALG0000001062319


Protein motifs (from Interpro)
Interpro ID Name
 IPR011991  ArsR-like helix-turn-helix domain
 IPR015163  Cdc6, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0030071 regulation of mitotic metaphase/anaphase transition IEA
 biological_processGO:0032467 positive regulation of cytokinesis IEA
 biological_processGO:0051984 positive regulation of chromosome segregation IEA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0051233 spindle midzone IEA
 molecular_functionGO:0019900 kinase binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex
CDK-mediated phosphorylation and removal of Cdc6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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