ENSGALG00000010623


Gallus gallus

Features
Gene ID: ENSGALG00000010623
  
Biological name :ORC1
  
Synonyms : ORC1 / origin recognition complex subunit 1
  
Possible biological names infered from orthology : Q13415 / Q9Z1N2
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 24455444
Gene end: 24470668
  
Corresponding Affymetrix probe sets: GgaAffx.11562.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017266
NCBI entrez gene - 424640     See in Manteia.
RefSeq - NM_001031286
RefSeq - XM_015291020
RefSeq Peptide - NP_001026457
swissprot - Q5ZMC5
Ensembl - ENSGALG00000010623
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 orc1ENSDARG00000039217Danio rerio
 ORC1ENSG00000085840Homo sapiens
 Orc1ENSMUSG00000028587Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDC6 / cell division cycle 6 / O89033* / Q99741* / Cell division control *ENSGALG000000365197


Protein motifs (from Interpro)
Interpro ID Name
 IPR001025  Bromo adjacent homology (BAH) domain
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR011991  ArsR-like helix-turn-helix domain
 IPR015163  Cdc6, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0000808 origin recognition complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005664 nuclear origin of replication recognition complex IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the ORC complex at the origin of replication
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008175 ORC5 / origin recognition complex subunit 5 / O43913* / Q9WUV0*  / reaction / complex
 ENSGALG00000015800 ORC3 / origin recognition complex subunit 3 / Q9JK30* / Q9UBD5*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction






 

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