ENSDARG00000011488


Danio rerio

Features
Gene ID: ENSDARG00000011488
  
Biological name :sirt2
  
Synonyms : sirt2 / sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)
  
Possible biological names infered from orthology : NAD-dependent protein deacetylase sirtuin-2 / Q8IXJ6 / Q8VDQ8 / sirtuin 2
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 6786757
Gene end: 6807963
  
Corresponding Affymetrix probe sets: Dr.13057.1.S1_at (Zebrafish Array)   NM_199596_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000003412
NCBI entrez gene - 322309     See in Manteia.
RefSeq - NM_199596
RefSeq Peptide - NP_955890
swissprot - F1QE37
ZFIN ID - ZDB-GENE-030131-1028
Ensembl - ENSDARG00000011488
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SIRT2ENSGALG00000029761Gallus gallus
 SIRT2ENSG00000068903Homo sapiens
 Sirt2ENSMUSG00000015149Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sirt3 / sirtuin 3 / Q8R104* / Q9NTG7*ENSDARG0000003581940
si:dkey-103i16.6ENSDARG0000006289337


Protein motifs (from Interpro)
Interpro ID Name
 IPR003000  Sirtuin family
 IPR017328  Sirtuin, class I
 IPR026590  Sirtuin family, catalytic core domain
 IPR026591  Sirtuin, catalytic core small domain superfamily
 IPR029035  DHS-like NAD/FAD-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016575 histone deacetylation IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017136 NAD-dependent histone deacetylase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070403 NAD+ binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium increased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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