ENSDARG00000012387


Danio rerio

Features
Gene ID: ENSDARG00000012387
  
Biological name :pdha1a
  
Synonyms : pdha1a / pyruvate dehydrogenase E1 alpha 1 subunit a
  
Possible biological names infered from orthology : P08559 / P29803 / P35486 / P35487 / PDHA1 / PDHA2 / pyruvate dehydrogenase E1 alpha 1 / pyruvate dehydrogenase E1 alpha 1 subunit / pyruvate dehydrogenase E1 alpha 2 subunit / Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 24031314
Gene end: 24044877
  
Corresponding Affymetrix probe sets: Dr.25869.1.S1_at (Zebrafish Array)   Dr.2656.1.A1_at (Zebrafish Array)   NM_213393_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000139481
Ensembl peptide - ENSDARP00000024338
NCBI entrez gene - 406702     See in Manteia.
RefSeq - NM_213393
RefSeq - XM_005165134
RefSeq Peptide - NP_998558
swissprot - Q6P948
swissprot - A0A0R4IT09
ZFIN ID - ZDB-GENE-040426-2719
Ensembl - ENSDARG00000012387
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDHA1ENSGALG00000016430Gallus gallus
 PDHA1ENSG00000131828Homo sapiens
 PDHA2ENSG00000163114Homo sapiens
 Pdha1ENSMUSG00000031299Mus musculus
 Pdha2ENSMUSG00000047674Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pdha1b / pyruvate dehydrogenase E1 alpha 1 subunit b / PDHA1* / PDHA2* / P08559* / P29803* / P35486* / P35487* / pyruvate dehydrogenase E1 alpha 1* / pyruvate dehydrogenase E1 alpha 1 subun...ENSDARG0000001055585
bckdha / branched chain keto acid dehydrogenase E1, alpha polypeptide / P12694* / AC011462.1* / branched chain ketoacid dehydrogenase E1, alpha polypeptide*ENSDARG0000004055524


Protein motifs (from Interpro)
Interpro ID Name
 IPR001017  Dehydrogenase, E1 component
 IPR017597  Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y
 IPR029061  Thiamin diphosphate-binding fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006086 acetyl-CoA biosynthetic process from pyruvate IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEA


Pathways (from Reactome)
Pathway description
Regulation of pyruvate dehydrogenase (PDH) complex
Glyoxylate metabolism and glycine degradation
Signaling by Retinoic Acid
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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