ENSDARG00000012763


Danio rerio

Features
Gene ID: ENSDARG00000012763
  
Biological name :arl13b
  
Synonyms : ADP-ribosylation factor-like 13b / arl13b / Q8JHI3
  
Possible biological names infered from orthology : ADP ribosylation factor like GTPase 13B / ADP-ribosylation factor-like protein 13B / Q3SXY8 / Q640N2
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 33668236
Gene end: 33694795
  
Corresponding Affymetrix probe sets: Dr.9405.1.S1_at (Zebrafish Array)   NM_173272_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000110549
Ensembl peptide - ENSDARP00000092960
NCBI entrez gene - 286784     See in Manteia.
RefSeq - NM_173272
RefSeq Peptide - NP_775379
swissprot - B8JIH7
swissprot - Q8JHI3
ZFIN ID - ZDB-GENE-021217-3
Ensembl - ENSDARG00000012763
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARL13BENSGALG00000015412Gallus gallus
 ARL13BENSG00000169379Homo sapiens
 Arl13bENSMUSG00000022911Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arl13a / ADP-ribosylation factor-like 13A / Q5H913* / Q9D416* / ADP ribosylation factor like GTPase 13A* / ADP-ribosylation factor-like protein 13A *ENSDARG0000005257529
arfrp1 / ADP-ribosylation factor related protein 1 / Q13795* / Q8BXL7*ENSDARG0000005785713


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007224 smoothened signaling pathway ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0021532 neural tube patterning ISS
 biological_processGO:0021830 interneuron migration from the subpallium to the cortex ISS
 biological_processGO:0021943 formation of radial glial scaffolds ISS
 biological_processGO:0035845 photoreceptor cell outer segment organization IMP
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:1905515 non-motile cilium assembly ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005929 cilium IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0060170 ciliary membrane ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
ARL13B-mediated ciliary trafficking of INPP5E


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000092 axis axis decreased length , abnormal
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 ZFA:0000114 heart heart bilateral symmetry , abnormal
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 ZFA:0000121 lateral plate mesoderm lateral plate mesoderm bilateral symmetry , abnormal
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 ZFA:0000150 pronephric duct pronephric duct motile cilium decreased length , abnormal
pronephric duct lacks all parts of type pronephric duct motile cilium, abnormal
pronephric duct cilium decreased length , abnormal
pronephric duct cilium decreased amount , abnormal
pronephric duct increased diameter , abnormal
pronephric duct cilium disoriented , abnormal
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 ZFA:0000151 pronephros pronephros cystic , abnormal
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 ZFA:0000155 somite somite increased width , abnormal
somite cilium decreased length , abnormal
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 ZFA:0000163 renal system renal system cilium spatial pattern , abnormal
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 ZFA:0000529 kidney kidney cystic , abnormal
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 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism curved ventral , abnormal
whole organism curved , abnormal
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 ZFA:0001115 trunk trunk increased width , abnormal
trunk curved ventral , abnormal
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 ZFA:0001117 post-vent region post-vent region curved , abnormal
post-vent region increased curvature , abnormal
post-vent region curved ventral , abnormal
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 ZFA:0001557 pronephric glomerulus pronephric glomerulus cystic , abnormal
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 ZFA:0001558 pronephric tubule pronephric tubule cystic , abnormal
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 ZFA:0009127 photoreceptor cell photoreceptor cell photoreceptor cell cilium decreased length , abnormal
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 ZFA:0009275 retinal rod cell retinal rod cell photoreceptor outer segment decreased length , abnormal
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 ZFA:0009367 neuromast hair cell neuromast hair cell kinocilium decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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