ENSDARG00000014479


Danio rerio

Features
Gene ID: ENSDARG00000014479
  
Biological name :ptf1a
  
Synonyms : pancreas specific transcription factor, 1a / ptf1a / Q7ZSX3
  
Possible biological names infered from orthology : Q7RTS3 / Q9QX98
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 29710857
Gene end: 29711761
  
Corresponding Affymetrix probe sets: DrAffx.1.60.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000011265
NCBI entrez gene - 368662     See in Manteia.
swissprot - Q7ZSX3
ZFIN ID - ZDB-GENE-030616-579
Ensembl - ENSDARG00000014479
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTF1AENSGALG00000027144Gallus gallus
 PTF1AENSG00000168267Homo sapiens
 Ptf1aENSMUSG00000026735Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:dkey-34f9.3ENSDARG0000007781319
ferd3l / Fer3-like bHLH transcription factor / Q923Z4* / Q96RJ6* / Fer3-like protein *ENSDARG0000009216014


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISS
 biological_processGO:0009887 animal organ morphogenesis IMP
 biological_processGO:0009888 tissue development ISS
 biological_processGO:0030154 cell differentiation IMP
 biological_processGO:0030902 hindbrain development ISS
 biological_processGO:0031016 pancreas development IMP
 biological_processGO:0031017 exocrine pancreas development ISS
 biological_processGO:0035881 amacrine cell differentiation IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0048384 retinoic acid receptor signaling pathway ISS
 biological_processGO:0048699 generation of neurons ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005667 transcription factor complex ISS
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001249 exocrine pancreas exocrine pancreas aplastic , abnormal
Show

 ZFA:0001369 anterior pancreatic bud anterior pancreatic bud decreased size , abnormal
Show

 ZFA:0001372 pancreatic duct pancreatic duct aplastic , abnormal
Show

 ZFA:0009092 exocrine cell exocrine cell absent , abnormal
Show

 ZFA:0009102 pancreatic B cell pancreatic B cell absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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