ENSDARG00000015515


Danio rerio

Features
Gene ID: ENSDARG00000015515
  
Biological name :mc4r
  
Synonyms : B0V1P1 / mc4r / melanocortin 4 receptor
  
Possible biological names infered from orthology : Melanocortin receptor 4 / P32245 / P56450
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 27932781
Gene end: 27933864
  
Corresponding Affymetrix probe sets: Dr.20030.1.S1_at (Zebrafish Array)   NM_173278_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000027547
NCBI entrez gene - 286833     See in Manteia.
RefSeq - NM_173278
RefSeq Peptide - NP_775385
swissprot - B0V1P1
ZFIN ID - ZDB-GENE-021223-2
Ensembl - ENSDARG00000015515
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MC4RENSGALG00000012907Gallus gallus
 MC4RENSG00000166603Homo sapiens
 Mc4rENSMUSG00000047259Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mc5ra / melanocortin 5a receptor / MC5R* / P33032* / melanocortin 5 receptor*ENSDARG0000003134868
mc5rb / melanocortin 5b receptor / MC5R* / P33032* / melanocortin 5 receptor*ENSDARG0000005494666
mc3r / melanocortin 3 receptor / P33033* / P41968* / Melanocortin receptor 3 *ENSDARG0000002136963
mc1r / melanocortin 1 receptor / Q01727* / Melanocyte-stimulating hormone receptor *ENSDARG0000002023752
mc2r / melanocortin 2 receptor / Q01718* / Q64326*ENSDARG0000005494943


Protein motifs (from Interpro)
Interpro ID Name
 IPR000155  Melanocortin 4 receptor
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001671  Melanocortin/ACTH receptor
 IPR001908  Melanocortin receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006112 energy reserve metabolic process IDA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IDA
 biological_processGO:0030819 obsolete positive regulation of cAMP biosynthetic process IDA
 biological_processGO:0040008 regulation of growth IGI
 biological_processGO:0097009 energy homeostasis IDA
 biological_processGO:2000252 negative regulation of feeding behavior IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004977 melanocortin receptor activity IDA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism increased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000069307 pomcb / proopiomelanocortin b / POMC* / P01193* / P01189* / proopiomelanocortin* / pro-opiomelanocortin-alpha*  / complex / reaction
 ENSDARG00000043135 pomca / proopiomelanocortin a / POMC* / P01193* / P01189* / proopiomelanocortin* / pro-opiomelanocortin-alpha*  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr