ENSDARG00000054949


Danio rerio

Features
Gene ID: ENSDARG00000054949
  
Biological name :mc2r
  
Synonyms : mc2r / melanocortin 2 receptor
  
Possible biological names infered from orthology : Q01718 / Q64326
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 30575901
Gene end: 30577136
  
Corresponding Affymetrix probe sets: Dr.24964.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000071699
swissprot - F1Q9X5
ZFIN ID - ZDB-GENE-030502-2
Ensembl - ENSDARG00000054949
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MC2RENSGALG00000035569Gallus gallus
 MC2RENSG00000185231Homo sapiens
 Mc2rENSMUSG00000045569Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mc4r / B0V1P1 / melanocortin 4 receptor / P32245* / P56450* / Melanocortin receptor 4 *ENSDARG0000001551546
mc3r / melanocortin 3 receptor / P33033* / P41968* / Melanocortin receptor 3 *ENSDARG0000002136944
mc5rb / melanocortin 5b receptor / MC5R* / P33032* / melanocortin 5 receptor*ENSDARG0000005494643
mc5ra / melanocortin 5a receptor / MC5R* / P33032* / melanocortin 5 receptor*ENSDARG0000003134841
mc1r / melanocortin 1 receptor / Q01727* / Melanocyte-stimulating hormone receptor *ENSDARG0000002023738


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001671  Melanocortin/ACTH receptor
 IPR001908  Melanocortin receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0030325 adrenal gland development IMP
 biological_processGO:0033555 multicellular organismal response to stress IEP
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004977 melanocortin receptor activity IEA
 molecular_functionGO:0004978 corticotropin receptor activity IDA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000043135 pomca / proopiomelanocortin a / POMC* / P01193* / P01189* / proopiomelanocortin* / pro-opiomelanocortin-alpha*  / reaction / complex
 ENSDARG00000069307 pomcb / proopiomelanocortin b / POMC* / P01193* / P01189* / proopiomelanocortin* / pro-opiomelanocortin-alpha*  / complex / reaction






 

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