ENSDARG00000016143


Danio rerio

Features
Gene ID: ENSDARG00000016143
  
Biological name :xiap
  
Synonyms : xiap / X-linked inhibitor of apoptosis
  
Possible biological names infered from orthology : baculoviral IAP repeat containing 8 / BIRC8 / P98170 / Q60989 / Q96P09
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 28473173
Gene end: 28483419
  
Corresponding Affymetrix probe sets: Dr.12645.1.S1_at (Zebrafish Array)   NM_194396_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000018322
NCBI entrez gene - 373108     See in Manteia.
RefSeq - NM_194396
RefSeq Peptide - NP_919377
swissprot - F1QMW2
ZFIN ID - ZDB-GENE-030825-7
Ensembl - ENSDARG00000016143
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 XIAPENSGALG00000008491Gallus gallus
 BIRC8ENSG00000163098Homo sapiens
 XIAPENSG00000101966Homo sapiens
 XiapENSMUSG00000025860Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
birc2 / baculoviral IAP repeat containing 2 / BIRC3* / Q13489* / Q13490* / Q62210* / baculoviral IAP repeat containing 3* / Baculoviral IAP repeat-containing protein 2 *ENSDARG0000004461938
birc7 / baculoviral IAP repeat containing 7 / A2AWP0* / Q96CA5* / Baculoviral IAP repeat-containing protein 7 Baculoviral IAP repeat-containing protein 7 30 kDa subunit*ENSDARG0000005808228


Protein motifs (from Interpro)
Interpro ID Name
 IPR001370  BIR repeat
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
SMAC binds to IAPs
SMAC-mediated dissociation of IAP:caspase complexes
Deactivation of the beta-catenin transactivating complex
RIPK1-mediated regulated necrosis
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Regulation of necroptotic cell death
Regulation of PTEN localization
Regulation of PTEN stability and activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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