ENSDARG00000016173


Danio rerio

Features
Gene ID: ENSDARG00000016173
  
Biological name :cct3
  
Synonyms : cct3 / chaperonin containing TCP1, subunit 3 (gamma)
  
Possible biological names infered from orthology : chaperonin containing TCP1 subunit 3 / P49368 / P80318
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 30408697
Gene end: 30421275
  
Corresponding Affymetrix probe sets: Dr.2417.1.S1_at (Zebrafish Array)   NM_173250_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000004738
NCBI entrez gene - 192327     See in Manteia.
RefSeq - NM_173250
RefSeq Peptide - NP_775357
swissprot - Q7T2P2
ZFIN ID - ZDB-GENE-020419-5
Ensembl - ENSDARG00000016173
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039205Gallus gallus
 CCT3ENSG00000163468Homo sapiens
 Cct3ENSMUSG00000001416Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012719  T-complex protein 1, gamma subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0046671 negative regulation of retinal cell programmed cell death IMP
 biological_processGO:0048048 embryonic eye morphogenesis IMP
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005832 chaperonin-containing T-complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IBA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000084 yolk yolk circular , abnormal
yolk grey , abnormal
yolk quality , abnormal
Show

 ZFA:0000106 extension extension decreased thickness , abnormal
extension aplastic , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye quality , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
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 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0000123 liver liver hypoplastic , abnormal
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 ZFA:0000282 sensory system sensory system quality , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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