ENSMUSG00000001416


Mus musculus

Features
Gene ID: ENSMUSG00000001416
  
Biological name :Cct3
  
Synonyms : Cct3 / chaperonin containing Tcp1, subunit 3 (gamma) / P80318
  
Possible biological names infered from orthology : chaperonin containing TCP1 subunit 3 / P49368
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 88297116
Gene end: 88321767
  
Corresponding Affymetrix probe sets: 10493193 (MoGene1.0st)   1416024_x_at (Mouse Genome 430 2.0 Array)   1426067_x_at (Mouse Genome 430 2.0 Array)   1439679_at (Mouse Genome 430 2.0 Array)   1448178_a_at (Mouse Genome 430 2.0 Array)   1449645_s_at (Mouse Genome 430 2.0 Array)   1451915_at (Mouse Genome 430 2.0 Array)   1459987_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000126109
Ensembl peptide - ENSMUSP00000130616
Ensembl peptide - ENSMUSP00000131113
Ensembl peptide - ENSMUSP00000131250
Ensembl peptide - ENSMUSP00000001452
NCBI entrez gene - 12462     See in Manteia.
MGI - MGI:104708
RefSeq - NM_009836
RefSeq Peptide - NP_033966
swissprot - Q3U4U6
swissprot - E9Q133
swissprot - F6Q609
swissprot - F6ZVG8
swissprot - P80318
swissprot - Q3U0I3
Ensembl - ENSMUSG00000001416
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cct3ENSDARG00000016173Danio rerio
 ENSGALG00000039205Gallus gallus
 CCT3ENSG00000163468Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012719  T-complex protein 1, gamma subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0007339 binding of sperm to zona pellucida IDA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IEA
 biological_processGO:0046931 pore complex assembly IMP
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:1901998 toxin transport IMP
 biological_processGO:1904871 positive regulation of protein localization to Cajal body IEA
 biological_processGO:1904874 positive regulation of telomerase RNA localization to Cajal body IEA
 cellular_componentGO:0002199 zona pellucida receptor complex IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005832 chaperonin-containing T-complex IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0044297 cell body IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0006206 embryonic lethality before turning of embryo "death anytime after somite formation but before embryo turning (E8 to less than E9)" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: CbfbTgTn(sb-cHS4,Tyr)2512E-2Ove/CbfbTgTn(sb-cHS4,Tyr)2512E-2Ove
Genetic Background: FVB/N-CbfbTgTn(sb-cHS4,Tyr)2512E-2Ove

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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