ENSG00000163468


Homo sapiens

Features
Gene ID: ENSG00000163468
  
Biological name :CCT3
  
Synonyms : CCT3 / chaperonin containing TCP1 subunit 3 / P49368
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q22
Gene start: 156308968
Gene end: 156367873
  
Corresponding Affymetrix probe sets: 200910_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357245
Ensembl peptide - ENSP00000388799
Ensembl peptide - ENSP00000435026
Ensembl peptide - ENSP00000434481
Ensembl peptide - ENSP00000434232
Ensembl peptide - ENSP00000431543
Ensembl peptide - ENSP00000413431
Ensembl peptide - ENSP00000413308
Ensembl peptide - ENSP00000295688
Ensembl peptide - ENSP00000357241
Ensembl peptide - ENSP00000357242
NCBI entrez gene - 7203     See in Manteia.
OMIM - 600114
RefSeq - NM_001008800
RefSeq - NM_005998
RefSeq Peptide - NP_001008800
RefSeq Peptide - NP_005989
swissprot - E9PM09
swissprot - B4DUR8
swissprot - P49368
swissprot - Q5SZW8
swissprot - Q5SZX6
swissprot - E9PRN0
swissprot - Q5SZX9
swissprot - E9PRM9
swissprot - E9PRC8
swissprot - E9PQ35
Ensembl - ENSG00000163468
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cct3ENSDARG00000016173Danio rerio
 ENSGALG00000039205Gallus gallus
 Cct3ENSMUSG00000001416Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012719  T-complex protein 1, gamma subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0007339 binding of sperm to zona pellucida IEA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IMP
 biological_processGO:0046931 pore complex assembly IEA
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:1901998 toxin transport IEA
 biological_processGO:1904871 positive regulation of protein localization to Cajal body IMP
 biological_processGO:1904874 positive regulation of telomerase RNA localization to Cajal body IMP
 cellular_componentGO:0002199 zona pellucida receptor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005832 chaperonin-containing T-complex TAS
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0005874 microtubule IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0044297 cell body IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IPI
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Association of TriC/CCT with target proteins during biosynthesis
BBSome-mediated cargo-targeting to cilium
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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