ENSDARG00000017891


Danio rerio

Features
Gene ID: ENSDARG00000017891
  
Biological name :tcp1
  
Synonyms : t-complex 1 / tcp1
  
Possible biological names infered from orthology : P11983 / P17987 / T-complex protein 1 subunit alpha
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 2421313
Gene end: 2443881
  
Corresponding Affymetrix probe sets: Dr.749.1.S1_at (Zebrafish Array)   NM_131230_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000104575
Ensembl peptide - ENSDARP00000148755
NCBI entrez gene - 30477     See in Manteia.
RefSeq - NM_131230
RefSeq Peptide - NP_571305
swissprot - Q803P2
swissprot - Q9W792
ZFIN ID - ZDB-GENE-990714-24
Ensembl - ENSDARG00000017891
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TCP1ENSGALG00000011637Gallus gallus
 TCP1ENSG00000120438Homo sapiens
 Tcp1ENSMUSG00000068039Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012715  T-complex protein 1, alpha subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005832 chaperonin-containing T-complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IBA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle decreased size , abnormal
Show

 ZFA:0000008 brain brain necrotic , abnormal
brain morphology , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk grey , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
eye necrotic , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
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 ZFA:0000114 heart heart quality , abnormal
heart edematous , abnormal
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 ZFA:0000123 liver liver hypoplastic , abnormal
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 ZFA:0000217 inner ear inner ear quality , abnormal
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 ZFA:0001094 whole organism whole organism bent , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head necrotic , abnormal
Show

 ZFA:0001115 trunk trunk necrotic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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