ENSMUSG00000068039


Mus musculus

Features
Gene ID: ENSMUSG00000068039
  
Biological name :Tcp1
  
Synonyms : P11983 / T-complex protein 1 subunit alpha / Tcp1
  
Possible biological names infered from orthology : P17987 / t-complex 1
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A1
Gene start: 12915701
Gene end: 12925067
  
Corresponding Affymetrix probe sets: 10441797 (MoGene1.0st)   10441811 (MoGene1.0st)   10441813 (MoGene1.0st)   1448122_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000086418
Ensembl peptide - ENSMUSP00000116108
Ensembl peptide - ENSMUSP00000116511
NCBI entrez gene - 21454     See in Manteia.
MGI - MGI:98535
RefSeq - NM_001290712
RefSeq - NM_013686
RefSeq Peptide - NP_001277641
RefSeq Peptide - NP_038714
swissprot - F2Z483
swissprot - P11983
Ensembl - ENSMUSG00000068039
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tcp1ENSDARG00000017891Danio rerio
 TCP1ENSGALG00000011637Gallus gallus
 TCP1ENSG00000120438Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012715  T-complex protein 1, alpha subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0007339 binding of sperm to zona pellucida IDA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IEA
 biological_processGO:0044053 translocation of peptides or proteins into host cell cytoplasm IMP
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051973 positive regulation of telomerase activity IEA
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:0090666 scaRNA localization to Cajal body IEA
 biological_processGO:1901998 toxin transport IMP
 biological_processGO:1904851 positive regulation of establishment of protein localization to telomere IEA
 biological_processGO:1904871 positive regulation of protein localization to Cajal body IEA
 biological_processGO:1904874 positive regulation of telomerase RNA localization to Cajal body IEA
 biological_processGO:2000109 regulation of macrophage apoptotic process IMP
 cellular_componentGO:0000242 pericentriolar material IDA
 cellular_componentGO:0000792 heterochromatin IEA
 cellular_componentGO:0001669 acrosomal vesicle IDA
 cellular_componentGO:0002199 zona pellucida receptor complex IDA
 cellular_componentGO:0005720 nuclear heterochromatin IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005832 chaperonin-containing T-complex IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0044297 cell body IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IBA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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