ENSDARG00000018902


Danio rerio

Features
Gene ID: ENSDARG00000018902
  
Biological name :pes
  
Synonyms : P79741 / pes / pescadillo
  
Possible biological names infered from orthology : O00541 / PES1 / Pescadillo homolog / pescadillo ribosomal biogenesis factor 1 / Q9EQ61
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 12836913
Gene end: 12865386
  
Corresponding Affymetrix probe sets: Dr.191.1.S1_at (Zebrafish Array)   NM_131030_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000026992
NCBI entrez gene - 30228     See in Manteia.
RefSeq - NM_131030
RefSeq Peptide - NP_571105
swissprot - P79741
ZFIN ID - ZDB-GENE-990415-206
Ensembl - ENSDARG00000018902
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PES1ENSGALG00000007778Gallus gallus
 PES1ENSG00000100029Homo sapiens
 Pes1ENSMUSG00000020430Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001357  BRCT domain
 IPR010613  Pescadillo


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ISS
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0008283 cell proliferation ISS
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0048709 oligodendrocyte differentiation IMP
 biological_processGO:0051726 regulation of cell cycle IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISS
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0030687 preribosome, large subunit precursor ISS
 cellular_componentGO:0070545 PeBoW complex ISS
 molecular_functionGO:0003723 RNA binding IBA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000012 central nervous system central nervous system has fewer parts of type oligodendrocyte myelin sheath, abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000059 postoptic commissure postoptic commissure morphology , abnormal
postoptic commissure astrocyte mislocalised , abnormal
Show

 ZFA:0000075 spinal cord spinal cord dorsal region has fewer parts of type oligodendrocyte , abnormal
spinal cord has fewer parts of type radial glial cell cell projection, abnormal
spinal cord apoptotic , abnormal
spinal cord ventral region has extra parts of type oligodendrocyte , abnormal
spinal cord grey matter has extra parts of type oligodendrocyte , abnormal
spinal cord white matter has fewer parts of type oligodendrocyte , abnormal
Show

 ZFA:0000084 yolk yolk circular , abnormal
yolk grey , abnormal
yolk increased size , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000108 fin fin decreased size , abnormal
Show

 ZFA:0000109 forebrain forebrain commissural neuron axon guidance disrupted , abnormal
forebrain morphology , abnormal
Show

 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
gut decreased size , abnormal
Show

 ZFA:0000123 liver liver quality , abnormal
liver decreased size , abnormal
Show

 ZFA:0000140 pancreas pancreas aplastic , abnormal
Show

 ZFA:0000435 cranial nerve II cranial nerve II decreased size , abnormal
cranial nerve II decreased thickness , abnormal
cranial nerve II defasciculated , abnormal
Show

 ZFA:0000445 optic tectum optic tectum decreased size , abnormal
Show

 ZFA:0000473 trunk musculature trunk musculature degenerate , abnormal
Show

 ZFA:0000672 hyomandibula hyomandibula decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism edematous , abnormal
whole organism lacks all parts of type pharyngeal arch 3-7 skeleton , abnormal
Show

 ZFA:0001108 anterior commissure anterior commissure morphology , abnormal
anterior commissure astrocyte mislocalised , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head opacity , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin morphology , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage fused with Meckels cartilage , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton decreased size , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas decreased size , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage oriented , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0001580 neurocranium neurocranium decreased length , abnormal
neurocranium increased thickness , abnormal
Show

 ZFA:0001617 otolith otolith morphology , abnormal
Show

 ZFA:0009076 oligodendrocyte oligodendrocyte distributed , abnormal
oligodendrocyte decreased amount , abnormal
oligodendrocyte plasma membrane disorganized , abnormal
oligodendrocyte axon misrouted , abnormal
oligodendrocyte axon split , abnormal
oligodendrocyte axonal growth cone collapsed , abnormal
Show

 ZFA:0009080 neurectodermal cell neurectodermal cell increased amount , abnormal
Show

 ZFA:0009292 radial glial cell radial glial cell cell projection disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003287 wdr12 / Q6NX08 / WD repeat domain 12 / Q9GZL7* / Q9JJA4*  / complex
 ENSDARG00000054980 ebna1bp2 / EBNA1 binding protein 2 / Q99848* / Q9D903* / Probable rRNA-processing protein EBP2 *  / complex






 

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