ENSDARG00000003287


Danio rerio

Features
Gene ID: ENSDARG00000003287
  
Biological name :wdr12
  
Synonyms : Q6NX08 / wdr12 / WD repeat domain 12
  
Possible biological names infered from orthology : Q9GZL7 / Q9JJA4
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 9630523
Gene end: 9646275
  
Corresponding Affymetrix probe sets: Dr.7725.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000004327
swissprot - Q6NX08
ZFIN ID - ZDB-GENE-030131-371
Ensembl - ENSDARG00000003287
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WDR12ENSGALG00000008470Gallus gallus
 WDR12ENSG00000138442Homo sapiens
 Wdr12ENSMUSG00000026019Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR012972  NLE
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR028599  WD repeat WDR12/Ytm1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000460 maturation of 5.8S rRNA IBA
 biological_processGO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ISS
 biological_processGO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ISS
 biological_processGO:0000470 maturation of LSU-rRNA IBA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0008283 cell proliferation ISS
 biological_processGO:0042254 ribosome biogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISS
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0030687 preribosome, large subunit precursor ISS
 cellular_componentGO:0070545 PeBoW complex ISS


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
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 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
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 ZFA:0001114 head head decreased width , abnormal
head decreased size , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018902 pes / P79741 / pescadillo / PES1* / O00541* / Q9EQ61* / Pescadillo homolog * / pescadillo ribosomal biogenesis factor 1*  / complex






 

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