ENSDARG00000018918


Danio rerio

Features
Gene ID: ENSDARG00000018918
  
Biological name :rad17
  
Synonyms : rad17 / RAD17 checkpoint clamp loader component
  
Possible biological names infered from orthology : O75943 / Q6NXW6
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 26188264
Gene end: 26199505
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000147188
Ensembl peptide - ENSDARP00000113849
Ensembl peptide - ENSDARP00000145091
NCBI entrez gene - 436934     See in Manteia.
RefSeq - NM_001002661
RefSeq - XM_005171833
RefSeq Peptide - NP_001002661
swissprot - Q6DG57
swissprot - A2BGQ6
ZFIN ID - ZDB-GENE-040718-409
Ensembl - ENSDARG00000018918
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAD17ENSGALG00000015571Gallus gallus
 RAD17ENSG00000152942Homo sapiens
 Rad17ENSMUSG00000021635Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004582  Checkpoint protein Rad17/Rad24
 IPR018324  Checkpoint protein Rad17/Rad24, fungi/metazoa
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0033314 mitotic DNA replication checkpoint IBA
 cellular_componentGO:0000790 nuclear chromatin IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0031389 Rad17 RFC-like complex IEA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0003689 DNA clamp loader activity IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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