ENSDARG00000019521


Danio rerio

Features
Gene ID: ENSDARG00000019521
  
Biological name :mpx
  
Synonyms : mpx / myeloid-specific peroxidase
  
Possible biological names infered from orthology : eosinophil peroxidase / Eosinophil peroxidase Eosinophil peroxidase light chain Eosinophil peroxidase heavy chain / EPX / lactoperoxidase / LPO / MPO / myeloperoxidase / Myeloperoxidase Myeloperoxidase light chain Myeloperoxidase heavy chain / P05164 / P11247 / P11678 / P22079 / P49290
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 7778870
Gene end: 7785945
  
Corresponding Affymetrix probe sets: Dr.9478.2.S1_at (Zebrafish Array)   Dr.9478.3.S1_a_at (Zebrafish Array)   Dr.9478.4.S1_at (Zebrafish Array)   Dr.9478.4.S1_a_at (Zebrafish Array)   NM_212779_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000043960
Ensembl peptide - ENSDARP00000103509
NCBI entrez gene - 337514     See in Manteia.
RefSeq - NM_001351837
RefSeq - NM_212779
RefSeq - XM_021479113
RefSeq Peptide - NP_001338766
RefSeq Peptide - NP_997944
swissprot - F1R9R1
swissprot - F1Q944
ZFIN ID - ZDB-GENE-030131-9460
Ensembl - ENSDARG00000019521
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039554Gallus gallus
 ENSGALG00000043254Gallus gallus
 EPXENSG00000121053Homo sapiens
 LPOENSG00000167419Homo sapiens
 MPOENSG00000005381Homo sapiens
 EpxENSMUSG00000052234Mus musculus
 LpoENSMUSG00000009356Mus musculus
 MpoENSMUSG00000009350Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
epx / eosinophil peroxidaseENSDARG0000001253537
pxdn / peroxidasin / Q3UQ28* / Q92626* / Peroxidasin homolog *ENSDARG0000009873331


Protein motifs (from Interpro)
Interpro ID Name
 IPR001073  C1q domain
 IPR008983  Tumour necrosis factor-like domain superfamily
 IPR010255  Haem peroxidase
 IPR019791  Haem peroxidase, animal type
 IPR029609  Myeloperoxidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006954 inflammatory response IMP
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0009617 response to bacterium IDA
 biological_processGO:0010310 regulation of hydrogen peroxide metabolic process IMP
 biological_processGO:0042742 defense response to bacterium IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0004601 peroxidase activity IDA
 molecular_functionGO:0020037 heme binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009048 granulocyte granulocyte absent , abnormal
Show

 ZFA:0009327 neutrophil neutrophil peroxidase activity decreased process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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