ENSDARG00000020217


Danio rerio

Features
Gene ID: ENSDARG00000020217
  
Biological name :cpsf4
  
Synonyms : cleavage and polyadenylation specific factor 4 / cpsf4
  
Possible biological names infered from orthology : Cleavage and polyadenylation specificity factor subunit 4 / O95639 / Q8BQZ5
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 40289418
Gene end: 40295255
  
Corresponding Affymetrix probe sets: Dr.62.1.S1_at (Zebrafish Array)   NM_131009_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000007713
NCBI entrez gene - 30203     See in Manteia.
RefSeq - NM_131009
RefSeq - XM_021469299
RefSeq Peptide - NP_571084
swissprot - F1Q949
ZFIN ID - ZDB-GENE-990415-180
Ensembl - ENSDARG00000020217
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CPSF4ENSGALG00000004714Gallus gallus
 CPSF4ENSG00000160917Homo sapiens
 Cpsf4ENSMUSG00000029625Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zc3h3 / zinc finger CCCH-type containing 3 / Q8CHP0* / Q8IXZ2*ENSDARG0000009075118


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR001878  Zinc finger, CCHC-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006378 mRNA polyadenylation IBA
 biological_processGO:0042462 eye photoreceptor cell development IMP
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 biological_processGO:0098789 pre-mRNA cleavage required for polyadenylation IBA
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0004521 endoribonuclease activity IBA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway
mRNA 3-end processing
Processing of Intronless Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton quality , abnormal
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 ZFA:0000107 eye eye quality , abnormal
eye decreased size , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
gut quality , abnormal
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 ZFA:0000114 heart heart quality , abnormal
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 ZFA:0000123 liver liver hypoplastic , abnormal
liver quality , abnormal
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 ZFA:0000152 retina retina quality , abnormal
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 ZFA:0000282 sensory system sensory system quality , abnormal
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 ZFA:0000292 surface structure surface structure quality , abnormal
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 ZFA:0001094 whole organism whole organism edematous , abnormal
whole organism lacks parts or has fewer parts of type pharyngeal arch cartilage , abnormal
whole organism lacks all parts of type pharyngeal arch 3-7 skeleton , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001161 pectoral fin pectoral fin quality , abnormal
pectoral fin decreased size , abnormal
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 ZFA:0001405 ethmoid cartilage ethmoid cartilage decreased size , abnormal
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 ZFA:0001461 chondrocranium cartilage chondrocranium cartilage decreased size , abnormal
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 ZFA:0001611 pharyngeal arch 2 pharyngeal arch 2 malformed , abnormal
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 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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